Every strength of Indonesian massage is just right.

▲ Milk bath for nourishing skin

▲ Nano-gold mask stimulates skin vitality

Thai massage can relax the muscles and bones.

I’d like to be a lovebird in heaven, and to grow together on the earth, two branches of one tree.. The Chinese Lunar New Year’s Eve is coming. On this special day, make her a SPA queen.

Text/Tao Xiaochun Figure/Jiang Qimin

Greece ningfu goddess theme SPA

Keywords: detoxification

Main raw materials: seawater and seaweed.

In Greek mythology, Nymph is the goddess in charge of the sea, lakes, springs and rivers. She lives in a silver cave at the bottom of the sea, with a beautiful voice and graceful dancing. She often soaks in seawater and has beautiful hair, smooth and flawless skin.

The Nymph-themed SPA takes care of the skin with the help of the rich resources and seaweed in the deep sea. Seawater is highly skin-friendly, can quickly penetrate into the inner layer of skin, deeply moisturize and activate skin, and enhance skin regeneration ability. Seaweed absorbs inorganic elements as nutrients every day, so it contains more natural inorganic elements than land plants, which can provide human needs, improve circulation, help the body detoxify and purify, replenish water and nourish.

Pure body and mind in blue sea water

The ocean foot bath containing marine microalgae appeared first. When your feet are gently immersed in the hot water mixed with lemon grass and green tea ingredients and light blue sea salt, it seems that your feet feel much relaxed at once, and the room is full of fresh and beautiful atmosphere of the sea. The micro algae from the Pacific Ocean make the next bath more relaxing and soothing. The natural Porphyridium and aloe essence contained in it can improve circulation, help the body to detoxify and purify, replenish water and nourish, and make the skin smoother. Being in it feels like floating on the blue water waves, and the sound of the waves lapping on the beach is lingering in my ears, so I can swim in the blue ocean to my heart’s content. This bath is especially suitable for people with poor sleep quality.

In order to further help skin exfoliate and detoxify, deep-sea white seaweed particles can be used to massage the body with lymphatic detoxification aromatherapy massage oil, which can stimulate lymphatic flow, detoxify and remove water, and reduce metabolic stagnation. The final nourishing and repairing body dressing is rich in spirulina essence, seaweed powder and soybean extract, which can effectively detoxify, improve edema, promote health, whiten and smooth skin, repair and resist aging, and nourish and moisturize.

During the whole nursing process, the room was very quiet except that the beautician occasionally asked softly about his feelings. The Indonesian massage used is different from the traditional Chinese acupressure acupoints. It uses more palm force and forearm force, and uses techniques such as palm strike, massage, kneading and reflection. The strength of each movement is just right, and each pressing place is a part that needs to be appeased urgently.

Cleopatra theme SPA

Keywords: anti-aging

Main raw materials: milk, pearls and honey.

Cleopatra Cleopatra is charming, glamorous and sexy. It is said that it was later discovered that Cleopatra bathed in milk on weekdays, scrubbed her body with sea salt, spread honey all over her body and face, and covered her face with gold foil every night, which eventually created a legend of immortality.

Pearl+milk+honey = young skin

The skin-beautifying effect of fresh milk bath has been described in the poem "Agar Jade Dew Wash and coagulate fat" as early as. And natural whitening and moisturizing milk+honey rich in vitamins+anti-aging holy pearl is a good combination of beautiful skin.

At this time, rose petals and long lemongrass floated in the white bathtub filled with warm water, and the beauty therapist slowly poured a can of milk and mixed it evenly. The room suddenly exudes a thick sweet smell, arousing the feeling of happiness from the heart. Gently pour a pool of flower water from the neck, shoulders, back and limbs … When taking a bath, soak the skin surface evenly in milk as far as possible, and gently massage it for 2~3 minutes, so that the nutrients in milk and pearl powder and honey can penetrate deep into the skin. When the skin is bathed in it, it will soon become tender, smooth, delicate, moist and whitening. This bubble bath is especially suitable for people with dry and dehydrated skin and mental fatigue.

It turns out that pearl milk can not only help skin exfoliate, but also relieve stress and relax. When used as body membrane, it can also lighten scars, improve skin color and make skin tender and smooth. During the process, the beauty therapist did not forget to remind that although milk is natural, safe and convenient, its effect is relatively short, and it can only stay on the skin surface, so it cannot completely replace other skin care products. In addition, milk contains high oil, so don’t forget to clean it before the end of nursing, so as to prevent clogging of pores and affect the normal function of the skin.

Can Cleopatra’s gold foil dressing really keep her face? Today, beauticians have improved it, using nano-pure gold combined with cytokines, active peptides, hydrolyzed silk protein and other ingredients to do facial care. After continuous use for one month, it has antioxidant, antibacterial and anti-inflammatory effects, stimulates self-renewal, makes skin shiny and transparent, and makes the feeling of firmness and brightness more obvious.

Thai royal herb

Health ball Massage

Keywords: anti-fatigue, relieving body ache

Main raw materials: a variety of herbs.

According to legend, this mysterious royal herbal secret recipe was only enjoyed by nobles in ancient times, and then it was gradually introduced to the people. It was found that the herbs used in it included tropical plants unique to Thailand, such as Casamona ginger, bergamot, lemon grass, tamarind fruit, derris, fennel, turmeric and white crane ganoderma lucidum. It makes use of the warm effect of hot-infiltrated herbal balls to penetrate the drug into the skin and supplement the energy elements belonging to the nursing part.

The refreshing effect of herbal balls

The massage technique in the process is quite unique. Massage important parts of the body with special aromatherapy oil. The beauty therapist uses the weight of his hands, arms, feet and his whole body, and uses unique methods such as pushing, pulling, stepping, pressing and pressing, and acts on muscle fascia and joints by pressing his feet, pressing his waist, stepping on his spine, and judo-style big back span, so as to relax muscles and bones, relieve stress and relax his mind.

The following hot herbal ball massage techniques are also very brilliant, especially the two hot herbal balls alternately act on the whole body skin, clicking, pressing, pushing, kneading or rotating, with various techniques. The beauty therapist will take turns to click and slide the herbal secret recipe health ball on the shoulder, neck, waist and other places that need to be comforted most. It is a little hot at first, but the skin will feel very comfortable after slowly adapting. Repeatedly several times, the herbal secret recipe health ball always keeps the appropriate temperature. Finally, the beautician will put the health ball on the waist and rub it back and forth. At this time, a hot air will be generated in the body, which can be kept for several hours.

Acknowledge the information provided by Yizhu SPA/ J SPA Yingmei Club.

Recently, MediaTek unveiled its new generation flagship 5G generative AI mobile chip Tianji 9300. The innovative all-core architecture design combined with the new generation AI processor APU and MediaTek’s unique cutting-edge technology, its powerful performance provided support for generative AI applications and created a vivid and substantial generative AI experience. At the same time, MediaTek shared resources with many AI companies in the industry, and jointly created an adequate AI ecosystem on the mobile side.

The brand-new seventh-generation AI processor APU 790 is born for generative AI.　　　　　

With the increasing demand of users for generative AI applications, the advantages of end-side generative AI such as convenience and security are highlighted. Of course, deploying the end-side AI language model requires strong AI computing power support.

Tianji 9300 is equipped with MediaTek’s seventh generation AI processor APU 790, which is designed for generative AI. It has a hardware-level generative AI engine, which can realize higher-speed and safer edge AI calculation, and deeply adapt to Transformer model for operator acceleration, with a speed eight times higher than that of the previous generation.

At the same time, the performance and energy efficiency of APU 790 have been significantly improved, and the integer operation and floating-point operation capabilities have been improved to twice that of the previous generation. Zurich ETHZv5.1 AI-Benchmark Mobile Soc scored 2109 points, and the AI performance successfully dominated the list, and the power consumption was reduced by 45%. With the support of powerful AI performance, images can be generated within 1 second. Tianji 9300′ s powerful AI computing power, innovative all-core CPU architecture and Immortalis-G720 GPU all lay a solid performance foundation for end-to-end running of generative AI.

At the same time, based on the characteristics of the large language model with hundreds of millions of parameters, MediaTek has developed the mixed-precision INT4 quantization technology, which, combined with the memory hardware compression technology of MediaTek, can make more efficient use of memory bandwidth, greatly reduce the terminal memory occupied by the large AI model, break through the memory limit of mobile phones for running the large AI language model end-to-end, and help the larger parameter model land on the end-side.

Based on the above, Tianqi 9300 landed a 7 billion-parameter AI language model on the side of vivo flagship mobile phone for the first time, with a processing speed of 20 Tokens per second. Not only that, MediaTek has broken through the industry limit, and has successfully run a large language model with 13 billion parameters on the end side with vivo. Even, Tianji 9300 has taken the lead in successfully running the AI language model with 33 billion parameters on mobile chips, leading the industry.

Tianji 9300 also supports multi-modal generative AI model, creating rich and interesting end-to-end experiences such as "Wen Sheng Poetry", "Wen Sheng Picture" and "Wen Sheng Interesting Picture".

It can be seen that Tianqi 9300′ s AI computing power and end-to-end generative AI capability are ahead of the industry, which is enough for users to be full of AI creativity anytime and anywhere.

The end-side skill expansion of generative AI model brings comprehensive and rich end-side generative AI experience.

Different from the cloud-side generative AI solution, due to the difference of hardware environment, the deployment of end-side generative AI also needs to consider factors such as mobile phone memory, storage capacity, and upper load limit. Therefore, MediaTek took the lead in proposing advanced solutions.

APU 790 supports NeuroPilot Fusion, an end-side skill expansion technology of generative AI model. It can continuously carry out LoRA (Low-Rank Adaptation) fusion on the end-side based on the basic big model. With the empowerment of hybrid AI, it can complete the fusion of n functions on the end-side based on one basic big model through cloud training, giving the basic big model more comprehensive and richer generative AI application capabilities.

For example, based on the "drawing GIF animation" function of the AI model end-side skill expansion technology, users can change different styles or even expressions according to a photo, and play an expression pack with a personal style, and the second expression pack is small.

NeuroPilot, an AI development platform, accelerates the end-side generative AI ecological layout.

Based on powerful AI computing power, advanced memory hardware compression technology and AI model end-side skill expansion technology, the APU 790 of Tianji 9300 has raised the speed and breadth of end-side generative AI to a new level. At the same time, in order to accelerate the deployment and popularization of generative AI in the end-side, MediaTek has also built a rich AI ecosystem with its AI development platform NeuroPilot, from the underlying hardware to the tool chain, model center and development ecosystem, helping the ecosystem to deploy end-side generative AI applications quickly and efficiently.

NeuroPilot, the AI development platform, supports leading-edge mainstream AI models such as Android, Meta LIama 2, Baidu ERNIE Bot Model and Hundred Rivers Intelligent Hundred Rivers Model.

More importantly, NeuroPilot has a complete and advanced tool chain, including low-rank adaptive fusion of NeuroPilot Compression, Speculative Decoding acceleration and model optimization and transformation technology.

MediaTek Tianji Developer Center can also provide one-stop developer resources for end-side generative AI landing, and share end-side model deployment cases to improve development efficiency. At present, more than 20 generative AI partners have joined the ecological co-construction.

MediaTek also works with industry contract partners to create a wonderful generative AI application experience. ArcSoft’s generative AI super-resolution technology is based on the edge computing power of Tianji 9300 APU, and its performance can be improved by 30% compared with the previous generation. When shooting at a magnification of 25 times, using the generative AI super-resolution technology, you can shoot more realistic image effects.

The generative AI semantic search technology of Extreme Sense Technology is also based on the edge computing ability of Tianji 9300 APU. Compared with the previous generation, the performance can be improved by 260%. For example, searching for photos in the photo album of a mobile phone and describing the content of the photos can accurately find the corresponding photos in milliseconds. Moreover, it can also be searched when the network is disconnected, and privacy will not be revealed.

Morpho’s video call real-time digital avatar generation technology is also based on the edge computing ability of Tianji 9300 APU, and its performance is improved by 26% compared with the previous generation. The general virtual portrait generator needs to manually select the appearance style, which takes time. However, based on the video call real-time digital avatar generation technology, the user can operate easily, and the digital avatar can be generated instantly only by opening a single frame of the camera.

Based on the edge computing ability of Tianji 9300 APU, the performance of Hui carp’s generative AI anti-glare technology can be improved by 60%. With the help of this technology, whether outdoors or indoors, if there is glare when shooting, you can eliminate glare interference as long as you relax and darken it.

It can be seen that under the trend of AI-side cloud convergence, Tianqi 9300 has shown comprehensive advantages in AI computing power, generative AI user experience and ecology, setting a new benchmark for a new generation of flagship end-to-end generative AI experience, and powerful generative AI will use Tianqi.

In addition, MediaTek and other pioneers of generative AI are constantly carrying out technological innovation and ecological layout, vigorously promoting hybrid AI computing, providing a unique and efficient solution for end-to-end generative AI deployment, and devoting themselves to promoting the widespread application of generative AI at the end-side, so that more users can experience personalized end-to-end AI applications and build a new panoramic intelligent experience, thus enabling technology to better serve the public.

　

Dancing, reading, fitness … Here, everyone can always find their own interesting activities, and walk into the "Neighborhood Home" activity center for the elderly at No.1 Yintian Changxing Lake, Changxing Community, Guankou Street, Liuyang City. It is a "base" for residents’ activities and a "conference hall" for residents to make suggestions and suggestions.

On April 26th, the "Good Neighborhood House" was officially unveiled with the cheers of everyone. Combined with local conditions, the street adheres to the way of party building leading, government leading and social participation, and builds the "Neighbourhood House" of Yintian Changxing Lake No.1, which realizes the construction of leisure activities venues integrating table tennis room, chess room, reading room and conference hall, and also provides services such as rest, drinking water and emergency charging to meet the diversified service needs of residents. At the same time, we will set up functional areas such as "Hello Neighbor Neighborhood Council" and Neighborhood Pioneer Post, extend the service "tentacles" of the Party organization from the general branch of the community to the districts and communities, and build red positions around the residents to realize community governance and residents’ service at the same frequency.

At the beginning of the construction, the general party branch of the community took the lead, with the participation of the community party branch, the industry committee, the property company, the members of the volunteer service team and the neighbors. Relying on the red platform of the community, the opinions of the masses were fully collected, and the residents’ representatives were mobilized to hold a good-neighborly meeting. After many discussions, it was finally unanimously decided that the community party branch would take the lead, the industry committee would raise funds, and the elderly association would assist in the management, so as to build a "good-neighborly house" of about 400 square meters on the eight overhead floors of the community. Really make "small things about people’s livelihood" a major event of "benefiting the people and benefiting the people".

At the opening ceremony of the Good Neighborhood House, the neighbors got together, singing and dancing. Accompanied by cheerful music, the performance kicked off in the opening dance of "Gathering Together". The dance "I Love Beautiful China" and other programs fully demonstrated the vitality and spiritual outlook of residents, and condensed and conveyed the positive energy among neighbors.

"Now, we have our own activity center. I dance when the weather is fine, and play chess and ball games when it rains. It’s really good …" Liu Yi, 58, said happily, waving a ping-pong bat, "Neighborhood House" has built a communication platform for residents, which has brought neighborhood relations closer, enhanced neighborhood feelings and further enhanced the sense of belonging and happiness of community residents.

Complete convenience service facilities, comfortable chairs and sofas, neatly arranged books … This warm and diverse neighborhood space closely revolves around the working idea of "co-construction, co-governance and sharing", and strives to extend services to people’s doorsteps and send warmth to people’s hearts.

In recent years, Guankou Street has actively built a "good neighbor’s house" activity position, and carried out neighborhood cultural activities in a normal way, so that "strangers" become "friends" and "friends" become "relatives". In the next step, Guankou Street will be guided by residents’ needs and rely on the "Good Neighborhood House" to carry out a variety of neighborhood activities to create a "happy life circle" with more family flavor and human touch. (Li Chunlan, Zhang Huizhi)

　　Mp3 is still here today, not the player of that year. The author’s impression of mp3 players began in high school. At that time, I was still using a heavy tape walkman, but "wearing headphones and hanging an mp3 player around my neck" has quietly become a campus fashion. At that time, the mp3 player was relatively large, connected with wired headphones, and looked from a distance, as if a stethoscope was hung around his neck.

　　At that time, I was lucky enough to experience my roommate’s mp3 player. It was very convenient to listen to songs, but it was inconvenient to find songs. The playing modes were only sequential playing, random playing and single loop. As an expert in using the rewind button of the walkman, I can judge the position and rewind time of a song according to the diameter of the tape reel, so the mp3 player is really "hehe" in my eyes.

　　Unfortunately, the good times didn’t last long. As soon as I graduated from high school, digital products such as walkman and tape were swept into the history museum along with the "rewind skills" that the author was proud of. But they were not killed by mp3 players, but by more advanced mobile phones. When I was in college, I used a mobile phone called "Nokia". Now children may not have heard of this brand. Back in those days, Nokia dominated the mobile phone industry with its Symbian intelligent system. It could not only listen to mp3 music, but also watch movies on a 2: 00-inch screen. Of course, more importantly, it saved money on mp3 and mp4 players.

　　However, the author’s college roommate Z still keeps the habit of using mp3 player. His mp3 player is a famous brand product in Japan, which costs thousands of dollars. It is said that the sound quality is excellent when used with a pair of German brand headphones costing more than 300 yuan. I’ve listened to it, too, and it’s really good, but if it’s too good to be wanted, it’s not too bad.

　　This Z student not only has an mp3 player, but also an mp4 player with a bigger screen than his face, which is the originator of the current big-screen mobile phone. At that time, I thought that it was just around the corner for mobile phones to replace mp3 and mp4 players, and the practice of Z students could only be simply evaluated as rich and powerful.

　　However, classmate Z gave me an unexpected answer. He said: "the computer is very powerful, right? But every time I turn on the computer, I always change my original intention unconsciously. For example, I originally wanted to watch a movie, but I played a game." I wanted to listen to music, but I got online. So I think that computers are used to play games online, mp4 players are used to watch movies, and mp3 players are used to listen to music. "

　　Some people may say that this is your classmate Z’s poor self-control. But just imagine, if you were given a computer with Internet access and full of movies, music and games to learn English, how long would you last without external supervision?

　　Once upon a time, the author was superstitious about self-control, but if we contact the supervision mechanism, we will find that in a relaxed environment, facing a world full of temptations, people basically have no self-control, and the probability of getting lost or even sinking is extremely high.

　　"The keyboard starts and ends, and you know exactly that 88 keys are there. You can’t go wrong … I like it, and I can easily cope with it … in that infinite spreading city, everything is there, but there is no end, no end at all. What I can’t see is the end of all this, the end of the world. " At the end of the movie legend of 1900, the hero 1900 uttered such a sigh.

　　I don’t know how many netizens have had similar ideas to 1900 when facing computers and mobile phones. Or perhaps, many netizens have lost themselves in the abyss of network information and forgotten the original intention of using computers and mobile phones before they have time to express their feelings.

　　Many years later, when I bought a certain brand of electronic paper book reader, I remembered the classmate who listened to music with mp3 player in college. Someone asked me: Why spend more than 800 yuan to buy a digital product that is slow to respond and can only read books?

　　To this, I can only answer: because my self-control is too poor.

　　As the saying goes, "a thousand dollars can’t buy old people to lose weight." Nowadays, many old people have joined the army to lose weight, and it seems that they will be healthy if they lose weight. Recently, a study published in the American Obesity magazine shows that the elderly’s deliberate weight loss may affect their bone health.

　　Body mass index BMI= the square of weight/height, which is an accepted standard to measure obesity. In this study, 77 students with an average BMI of 33.6 (usually 18.5≤ BMI index ≤ 23.9 old people with normal weight, more than 29.9 are severely obese) were given weight-loss intervention for 18 months, and the overall weight of the old people and the bone mineral density of the areas (total hip, femoral neck, lumbar vertebrae and trabecular bone) were monitored and scored at 18 months and 30 months. The results show that the decline of hip bone mineral density will last for one year after weight-loss intervention for elderly obese patients, whether they rebound or not. The study also found that fat loss and weight loss reduced the bone mineral density of hip and increased the risk of osteoporosis.

　　Gou Bo, a professor in the Department of Health Sciences of Xi ‘an Institute of Physical Education, said that if the elderly lose weight improperly, such as excessive diet control, resulting in insufficient nutrition intake, or lose weight too much and too fast, resulting in significant weight loss, it will lead to a decline in bone density. Older people do not have to lose weight if they are only slightly obese and have no obvious cardiovascular disease. If there are some contraindications to exercise, and it is not suitable for exercise to lose weight, you can seek nutrition, medical care and other methods to control your weight under the guidance of a doctor. If obesity is accompanied by other chronic diseases, lose some weight appropriately. In principle, adopt safe and effective methods to achieve the goal at a slower speed such as diet control and exercise.

　　Many old people find that even if they eat and exercise as much as when they were young, it is easy to "gain weight". The reason is that the basal metabolic rate and muscle mass of adults decrease year by year with age. Therefore, even if the elderly eat less, their digestion and absorption ability are poor, and the balance of energy in and out is still "less in and out", in which case it will be "fat".

　　Gou Bo emphasized that obesity will directly affect heart function and vascular health, and it is easy to suffer from various cardiovascular and cerebrovascular diseases. The ideal situation is to "gain muscle and lose fat" on the premise of ensuring basic nutrition.

　　Old people can’t take extreme measures to lose weight, let alone go on a diet like young people. We can start with the moderation and choice of dinner, eat some coarse grains instead of staple food, eat food with high protein content for breakfast, and control the staple food at about 2 Liang at noon. It is not recommended to choose diet pills or surgery to lose weight.

　　In sports, it is suggested that aerobic exercise should be combined with strength training, and it is best to take some soothing forms, such as Tai Ji Chuan, yoga, walking, etc. As long as you can persist every day and achieve a certain amount of exercise, you can lose weight completely.

　　Interviewed expert: Professor Gou Bo, Department of Health Sciences, Xi ‘an Institute of Physical Education

Dr. Guan Kang Kang You from the Department of Nuclear Medicine talks about thyroid gland.

1. What is pepsinogen?

Pepsinogen (PG) is the precursor of pepsin. According to its biochemical properties and immunogenicity, it can be divided into two subgroups. The immunogenicity of 1~5 components is the same, and it is called Pepsinogen I (PG I), which is mainly secreted by the main cells of gastric fundus gland and mucus neck cells. Components 6 and 7 are called pepsinogen Ⅱ(PGⅡ), which can be secreted by the main cells and mucus neck cells of gastric fundus gland, and also produced by mucus neck cells of pyloric gland of cardiac gland and gastric antrum and upper duodenum.

Usually, about 1% PG enters the blood circulation through the capillary of gastric mucosa, and the PG entering the blood circulation is very stable in the blood. Serum PG ⅰ and PG ⅱ reflect the number of glands and cells in gastric mucosa, and indirectly reflect the secretory function of different parts of gastric mucosa. When pathological changes occur in gastric mucosa, the content of serum PG also changes. Therefore, monitoring the concentration of PG in serum can be used as a means to monitor the status of gastric mucosa.

Detection of pepsinogen (PG), an early warning indicator of gastric cancer

1. Chronic atrophic gastritis is an important "transitional event" in gastric mucosa canceration.

Gastric cancer is one of the common malignant tumors in China, and its mortality ranks first among all kinds of malignant tumors. Its early diagnosis and early treatment have become the only way to improve the quality of life of patients and reduce the mortality. At present, the main methods for diagnosing gastric cancer are fiberoptic gastroscopy and upper gastrointestinal radiography, among which gastroscopy is called the "gold standard" for diagnosing gastric cancer.

At present, it is believed that partial atrophy can be reversed, and once it enters intestinal metaplasia, it is difficult to reverse it. Therefore, there is an urgent need for a tool that can keenly detect the atrophy of gastric mucosa. At this time, the detection of pepsinogen plays a powerful role.

When the gastric fundus gland atrophied, the number of main cells decreased and the level of PG ⅰ decreased. However, because there are more cells secreting PG ⅱ, PG ⅱ can still maintain a high level at this time, and the ratio of PG ⅰ to PG ⅱ decreased significantly. When atrophic gastritis is accompanied by intestinal metaplasia and gastric antrum gland extends to the stomach body, and pseudopyloric metaplasia of gastric fundus gland occurs, the level of PG ⅱ increases more, and the ratio of PG ⅰ to PG ⅱ decreases further. Therefore, the decrease of PG ⅰ level is a reliable sign of gastric fundus gland mucosa atrophy, and PG ⅰ/PG ⅱ profile reflects the degree of gastric fundus gland mucosa atrophy.

2. Helicobacter pylori infection is the initiating factor for the development of gastric cancer.

The occurrence of gastric cancer is the result of multiple factors. The multi-step hypothesis of gastric cancer, that is, from chronic non-atrophic gastritis (formerly known as chronic superficial gastritis) → atrophic gastritis → intestinal metaplasia → intraepithelial neoplasia (formerly known as dysplasia) → gastric cancer, has been generally accepted. Helicobacter pylori (Hp) infection has become the most important initiating factor, and Hp infection has been recognized as an independent risk factor for gastric cancer.

Therefore, active detection of Hp has become one of the important measures to prevent and treat gastric cancer. Hp detection is mainly divided into invasive and non-invasive methods. For Hp-positive infected people, the major guidelines have reached a consensus that Hp infection-related gastritis is an infectious disease and it is recommended to eradicate it.

Hp infection can also significantly affect the serum PG level. At the beginning, PG ⅰ and PG ⅱ both increased, and the increase of PG ⅱ was faster, then PG ⅰ/PG ⅱ decreased, and the larger the Hp infection focus, the greater the decrease of PG ⅰ/PG ⅱ. However, the results of pepsinogen test are lack of specificity, and special Hp test is still needed to judge whether Hp is infected or not.

Third, pepsinogen Ⅰ(PGⅠ),

The results of pepsinogen Ⅱ(PGⅡ) were analyzed as follows:

Four, "pepsinogen" test results misunderstanding:

Myth # 1: If only PG ⅰ is measured during physical examination, nearly 70% of the results are in the range of 40~70ng/mL, which seems to be lower than 70ng/mL on the surface, and gastric atrophy is suspected, but the results are difficult to explain because PG ⅱ and ratio are not measured. When PGⅡ is retested, the ratio of more than 90% is greater than 3. This kind of situation is due to the high incidence of chronic superficial gastritis in China population, which belongs to normal physiological gastric acid secretion insufficiency.

Myth 2: PG-positive means "stomach cancer theory": positive means people at high risk of stomach cancer. PG project is a simple screening project for gastric cancer in the early stage of physical examination, replacing X-ray and ultrasonic screening for gastric cancer. The main significance lies not in diagnosis but in early detection and prevention. Normal people are 15%PG positive, and those with PG positive have a high risk of developing gastric cancer, and the early detection rate of gastric cancer is 1%~2%.

Myth # 3: Pay attention to the change of reference range values of PG ⅰ and PG ⅱ, but not the ratio. Because the secretion of PG ⅰ in gastric mucosa changes greatly (above 70~800ng/mL) under the attack of inflammation, the secretion of PG ⅱ is relatively constant. When comparative value > 3, the degree of PG ⅰ increase can only be combined with clinical analysis to determine the type of gastric diseases. When comparative value < 3, it is suggested that further in-depth endoscopy or pathological sampling should be taken to confirm and warn the high risk of early gastric cancer, and follow-up monitoring should be carried out in the last five years. The incidence of gastric cancer was 2% in PG-positive patients who had no gastric cancer in the same year and in the following five years.

Five, Japan’s experience for reference ("ABC" method+endoscopic screening)

Our neighbor Japan, as a country with high incidence of gastric cancer, has done a very good job in early cancer screening. Their screening strategy for early cancer firmly grasps the two controllable factors of Hp infection and whether gastric fundus gland atrophy occurs.

The Kyoto Consensus of Japan made the following recommendations for the national early cancer screening strategy: first, for Hp infection, the Kyoto Consensus emphasized "shoot to kill", and after everyone sterilized and eradicated Hp, PG was evaluated. The ratio of PG ⅰ/PG ⅱ is ≤3.0, which is regarded as the critical diagnostic value of atrophic gastritis, and as the screening standard of high-risk population of gastric cancer.

Vi. A Long Way to Go-Strategies for Early Cancer Screening in China;

China has a large population base and the incidence of gastric cancer remains high, so it is imperative to find a simple, accurate and effective screening method for gastric cancer. In 2017, the China Consensus on Chronic Gastritis highly affirmed the value of PG, and the guidelines gave the following recommendations: The detection of serum pepsinogen (PG) ⅰ and ⅱ and gastrin -17 may help to judge whether there is gastric mucosal atrophy and its degree. Detection of serum PG ⅰ, PG ⅱ, PG ⅰ/PG ⅱ ratio combined with anti-Hp antibody is helpful for risk stratification management.

The Expert Consensus on Early Gastric Cancer Screening Process in China, published at the end of 2017, not only affirmed the value of serum PG, but also put forward a new gastric cancer screening scoring system, in which the elderly, male, Hp antibody positive, low pepsinogen ratio (PGR) and high serum 17(gastrin-17 (G-17) level are high risk factors for gastric cancer.

Among them, G-17 is a new item in China Guide. G-17 is an amidated gastrin synthesized and secreted by G cells in gastric antrum. Its main physiological function is to stimulate gastric acid secretion and promote the proliferation and differentiation of gastric mucosal cells. G-17 is one of the sensitive indexes to reflect the endocrine function of gastric antrum, which can indicate the atrophy of gastric antrum mucosa or whether there is abnormal proliferation. G-17 itself can also promote the occurrence and development of gastric cancer. When the serum G-17 level rises, it may indicate the risk of gastric cancer.

In addition, different from the Kyoto consensus, the consensus in China put forward the critical value of serological detection for the first time, that is, when PGR<3.89 and G-17> 1.50pmol/L, the risk of gastric cancer increased significantly. The critical value of PGR defined by Kyoto Consensus is ≤3.

According to the score, the guide divides the population into three groups: low risk, medium risk and high risk, and gives the screening strategy.

At the same time, however, we should also see the shortcomings of the China guidelines. The screening population is over 40 years old, and there are other risk factors such as high incidence area of gastric cancer, Hp infection, previous precancerous diseases of gastric cancer, first-degree relatives of gastric cancer patients, diet and so on. However, at present, the onset age of gastric cancer is getting earlier and earlier, and I believe it will definitely enter prospecting stage in the future.

To sum up, serum PG combined with Hp detection is helpful to evaluate the risk of gastric cancer, and can be used as a routine screening method for gastric cancer for ordinary people. However, it cannot replace gastroscopy, and gastroscopy is still strongly recommended for high-risk groups.

Original title: Clinical Significance of Detection of Pepsinogen (PG)

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　　Cctv newsOn January 19th, the joint prevention and control mechanism of the State Council held a press conference on epidemic prevention and control during the Spring Festival.

　　At the meeting, a reporter asked whether people who have not yet been infected with Covid-19 can safely return home for the New Year. What are the suggestions on protection? Do people who have recently been infected with Covid-19 still need protection when traveling?

　　Chang Zhaorui, a researcher at the Center for Disease Control and Prevention of China, said that people are generally susceptible to Covid-19. Some people who have not been infected do not rule out the influence of travel fatigue and frequent contacts during the Spring Festival, and the risk of infection will increase. It is suggested that relevant personnel should continue to do personal protection, keep regular work and rest, eat reasonably, exercise moderately, disinfect well and wear masks. The public who have been infected with Covid-19 should continue to do personal protection to prevent infection of other respiratory infectious diseases, including influenza.

Ashton Kutcher, the American movie star who plays Jobs, has just joined Lenovo Group. According to the USA-Today website, Kucher signed a cooperation agreement with Lenovo on the evening of 29th local time to serve as Lenovo’s product engineer and spokesperson.

Lenovo held a new product launch conference in Los Angeles at 7 o’clock that night, and launched the world’s first "legged" tablet computer &mdash; &mdash; Yoga tablet. The conference was broadcast live on Youtube for global users to watch. At the press conference, Kucher held a Yoga tablet computer, just like the way Jobs introduced Apple’s new products. After the conference, Kucher will meet Lenovo engineers and executives in China in the future.

Kucher introduces Lenovo Yoga tablet computer.

Kucher said at the press conference that modern people often encounter two situations in their daily lives: lying in bed and using a tablet computer is easy to slip into their face because of their hands; The battery of a tablet or smart phone is useless, so everyone has to bring a brick-like mobile power supply. These two common details made the audience laugh, which is indeed an experience that many people have had. The new products launched by Lenovo just solved these two problems: the small bracket liberated people’s hands; The battery life that can work continuously for 18 hours on a single charge can help people reduce the weight of their backpacks. In addition, you can also charge your smartphone with a tablet computer, and the USB interface on the tablet computer can easily achieve this.

Lenovo’s new tablet has 8-inch and 10-inch versions, and the price is $249 and $299 respectively. These two products will be available from October 30, just in time to "play against Taiwan" with the Apple tablet iPad Air, which was officially released on November 1. However, Lenovo’s products are much cheaper than Apple’s iPad Air, and the lowest price of the new generation iPad is $499.

Kucher, 35, graduated from the University of Iowa in the United States, majoring in biochemical engineering (but didn’t graduate). She was once kicked out of her dormitory because she was too noisy and crazy. However, he is now Walden Schmidt, the hero of the popular comedy Two and a Half Heroes, which was launched by CBS in the United States, and also a famous angel investor in Silicon Valley. In addition to Skype, Kucher’s investment also includes Foursquare, Flipboard and Path.

Kucher at the new product launch is very much like Jobs.

Kucher has also cooperated with Google and Apple. When talking about why he joined Lenovo, Kucher said, "Lenovo’s hardware is very, very good. I want to make their products as consumer-friendly as possible. " Kucher will make suggestions on the design and software of Yoga tablet.

USA-Today said that this cooperation is a prepared risk for both sides. And Kucher said that this is precisely the reason why he joined Lenovo. "If you look back on my career, you will find that I have always liked adventure &mdash; &mdash; Lenovo, too, "Kucher said.

Phoenix. com said that some fruit fans commented that Kucher had joined Lenovo: He should know more about Apple culture after playing Jobs, and now it’s a bit disappointing to advertise Lenovo for money. It seems that he is not a real fruit fan. Since he is not a fruit fan, no wonder he can’t play Jobs well.

Lenovo and Kucher did not disclose the salary of this cooperation.

Stills of the movie Jobs

Liam Neeson talks to the mystery man with a serious face.

1905 movie network news A few days ago, the action suspense film has met the audience in North America. The action scenes of life and death and the suspense reversal of wits have made the film gain excellent box office results and word of mouth after its release. With a series of films, liam neeson, who successfully created the screen to "rescue professional households", once again "returned to his old job". As an ordinary white-collar uncle, he was not only accidentally involved in a conspiracy, but also single-handedly searched for a mysterious passenger on the commuter train in new york and eliminated the danger, which was exciting and suspenseful.

The Commuter tells the story of Macaulay, the hero played by liam neeson, who meets the mysterious girl Joanna on his way home by commuter train in new york. Joanna offered Macaulay a tempting task &mdash; &mdash; Find out a passenger in the car and get a huge sum of cash in return. But in the process of searching, Macaulay gradually found himself not only involved in a deadly conspiracy, but also unable to quit, and a rescue operation full of suspense and excitement began. When the commuter train close to everyone’s life scene becomes a runaway and deadly journey, how Uncle Liam can solve the puzzles lurking in the commuter train and rescue the passengers is expected.

Liam Neeson turned into a white-collar uncle, running for his life.

With a series of screen roles to rescue relatives in distress, liam neeson deserves to be a "rescue specialist" in Hollywood. In Taken3 series films, he plays a retired agent who chases across many countries and rescues his daughter and wife from foreign evil organizations. Whether it is a sharp and professional lynching trial or a quick skill of one enemy and ten, the image of a loving father who is eager to save a woman and the fierce domineering of fighting violence with violence have made him numerous; In the movie, liam neeson, who plays the plainclothes air marshal, changed the battlefield again, fighting wits and wits with the hijackers lurking among the passengers at high altitude, reversing Gan Kun in the air at the peak of 10,000 meters, finding out the black hand behind the scenes from the clues, and at the same time, fighting hand-to-hand in the narrow cabin to rescue the passengers of the whole plane &hellip; &hellip;

It can be said that with a series of invincible rescue operations, Uncle Liam not only successfully created an IP movie with the theme of "rescue", but also made himself a leading figure in Hollywood action heroes and won fans all over the world to call him crazy.Different from films such as Taken3 and NON-STOP, the role played by liam neeson in The Commuter no longer has the aura of skills such as special agent and air marshal, but becomes a white-collar office worker. Playing an ordinary person in an action movie for the first time, he not only had to make a living, but also struggled with the complicated and demanding needs of his boss and customers. At the age of 60, he lost his job and lost his direction in life, and he didn’t know how to face his family and future. It is a challenge for talented liam neeson to play such an ordinary middle-aged man who is involved in a life-and-death rescue operation at the same time. In the film, liam neeson, who was laid off, was lured by the mysterious girl into a gambling conspiracy because of the pressure of life.

Liam neeson moved the wrench to rescue the commuter train.

Jaume serra, the director who has cooperated with liam neeson for four times, praised Uncle Liam’s performance. He recalled his experience in shooting The Commuter, saying, "Every day when shooting, I am like a child looking forward to a Christmas present, waiting for the performance surprise brought by Nelson. His style and his eyes, he can completely change and create new roles with various nuances."

Not only is it more interesting in acting, but the action scene of the film is also thrilling. In the closed tense and high-speed train space, liam neeson should not only race against time to crack the true identity of the man behind the scenes, but also use all props in the train to fight, constantly resolve the dangerous ambushes and rescue the passengers on the train. The gradual reversal of the plot and the rapid and sharp action scenes have all upgraded The Commuter’s performance and action scenes.

In addition to liam neeson, the film The Commuter also featured famous Hollywood movie stars Vera Farmiga, Patrick Wilson and sam neill, and was directed by NON-STOP’s Hollywood genius jaume serra. The film has been released in North America and is expected to be introduced to Chinese mainland in 2018.

When exploring the off-road capability of tank 300, let’s have a deep understanding of its unique drive system.

Officials claim that the tank 300 is equipped with three differential locks, but the key lies in its part-time 4wd design. In fact, because the front and rear axles are connected by hard connection in the four-wheel drive mode, in this case, we can’t simply think that the tank 300 has three independent locks. It essentially relies on two differential locks at the front and rear axles to provide torque distribution and stability.

Take tank 300 2023 2.0T fighters 02 as an example, this compact SUV is famous for its hard-core style and practical features. It has a body length of 4,730mm, a width of 2,020mm, a height of 1,947mm and a wheelbase of 2,750mm, providing passengers with spacious interior space. The curb weight is 2365kg, and it is equipped with a 2.0T turbocharged engine. The maximum power can reach 167kW, and the torque output is even more amazing, reaching 387Nm. With the 8-speed automatic manual transmission, this model can be used in off-road performance and daily driving.

In short, although the official propaganda mentioned three differential locks, in practice, the tank 300 mainly relies on the mechanical locking of its front and rear axles to deal with complex road conditions and provide excellent off-road experience.