Professor Yang Xichuan, Original Professor of Xichuan Xiaoliang Dermatology

| Editing/Typesetting: Fanny Editor: kiki&Jeing Audit: Li Yun

Fact is stranger than fiction. There are thousands of diseases in the world, which are particularly strange and rare?

Today, Xiao Liang, a boy♂ who is keen on studying the mysteries of the body, will take you close to science and learn about four bizarre and rare human diseases that may be unknown to 90% people (strange knowledge has increased again).

Please note that there is continuous high energy ahead, and timid students should be careful ~

NO.1 Shuren disease: hands and feet are covered with "branches and roots"

I’m sure you’ve all heard about vegetative state, but have you ever heard of Shuren? What do you think of first? The cute Groot in Marvel Comics’s movies?

(Source: dribbble/Hancooock)

The tree people in the movie can love each other, but in real life, the "tree people" have to suffer from "tree people’s disease".

Shuren’s disease, medically known as "epidermodysplasia verrucosa", is a rare hereditary skin disease caused by human papillomavirus (HPV) infection, which may be related to gene mutation. It usually begins between the ages of 4 and 8, and most often begins before the age of 20.

People with Shuren’s disease usually grow many sarcomas, maculae and papules that look like branches and roots on their hands and feet, which not only affect the appearance, but also make it inconvenient for daily life, and also turn into skin cancer with high winds.

(Indonesian man suffering from Shuren disease)

Unfortunately, there is no unified and effective solution to this disease at present. Some studies think that retinoids can improve it to some extent. In addition, patients should avoid excessive sun exposure, and if they are prone to cancer, they should be operated immediately or removed by other methods.

NO.2 Premature senility: 7-year-old age and 70-year-old appearance

Anti-aging is the pursuit of many people. Who doesn’t want to be younger and more energetic every year? However, in this world, some people actually get old and even die early at a young age because of a rare genetic disease-premature senility.

Art comes from life. It is said that the film "The Curious Case of Benjamin Button" (also known as "Rejuvenation") may be inspired by premature senility, but the time sequence is reversed. The hero of the film looks like an old man of 70 or 80 at birth. As time goes by, the people around him are getting older, but he is rejuvenating, getting younger and younger, and finally returning to the baby form and dying in the arms of an old lover.

(Source: Movie "The Curious Case of Benjamin Button")

If the protagonist’s life is a bizarre movie, then in reality, patients with premature senility live a life like pressing the acceleration button, aging faster than their peers, feeling the rapid failure of every body organ every day, and dying before they bloom.

There are some heartbreaking facts about premature senility:

● Premature senility in adults: Patients usually develop normally before puberty. At the age of 20-30, they begin to have aging characteristics such as skin wrinkles, muscle atrophy, gray hair and shedding, and the average age of death is 47 years old.

● Premature senility in children: The patient is normal at birth, but after birth, the appearance and body organs will accelerate the aging and decline, and with the increase of age, he will suffer from various diseases such as cardiovascular disease, and the average age of death is only 13 years old.

(patients with premature senility)

NO.3 Vampire: You can only live in darkness.

Legend has it that there are zombies in the East and vampires in the West. Speaking of vampires, you may think of the handsome "ghosts" of noble Leng Yan in film and television dramas. In real life, many people are willing to believe that vampires exist in some corner of the world, but in the medical field, "vampires" really may exist, and they are porphyria patients.

You can slide left and right to view the picture, but it is recommended to slide carefully!

Porphyrin (bD lí n) disease is a rare metabolic disease caused by the lack of enzyme activity in heme biosynthesis pathway, which leads to abnormal increase of porphyrin or its precursor concentration and accumulation in tissues, resulting in cell damage. In 2020, experts in the diagnosis and treatment of porphyria agreed to divide porphyria into the following categories:

(Source: Literature [4])

When the medical profession knew nothing about porphyria hundreds of years ago, patients with porphyria were often considered as legendary vampires, which may be because some symptoms of porphyria are very similar to the image of vampires.

photophobia

People suffering from porphyria will be as afraid to be exposed to the sun as vampires, because they will get sick when they see light, and their skin will have photosensitive reaction, blisters, scars, deformities, etc., and in severe cases, they may be accompanied by the loss of fingers, eyelids, nose and ears.

"bloodthirsty"

Unlike vampires who directly suck people’s necks to drink blood, porphyria patients are "bloodthirsty" by blood transfusion to achieve treatment and relief.

Look different from ordinary people

The high level of porphyrin in red blood cells of patients with porphyria can lead to hemolysis, and severe hemolysis often leads to anemia, so it may cause pallor.

However, people with congenital erythropoietic porphyria will show red or brown color in their teeth, bones and urine due to excessive porphyrin, and they will fluoresce when exposed to ultraviolet rays, which really looks a bit like vampires who have just eaten their children.

NO.4 werewolf syndrome: a real hairy child

Everyone has Mao Mao, but people with werewolf syndrome have a lot of Mao Mao.

However, this werewolf is not a werewolf. The so-called werewolf syndrome actually refers to "congenital systemic hirsutism". The patient’s whole body is covered with thick hair, which is beyond the normal physiological range of the same age, gender and race, and seems to be the image of a werewolf in our impression. In addition to excessive hair, it is usually accompanied by facial deformities.

(Source: Literature [6])

The prevalence rate of werewolf syndrome is extremely low, and it was once considered as an "atavism" phenomenon. However, at present, most studies believe that patients suffer from this disease because of unknown genetic defects.

Patients with the above diseases are often noticed by people in their daily lives because of their abnormal appearance, but who doesn’t want to be healthy and safe in life, and who would like to do so if they could start over.

When you meet them in your life, please be less discriminating and misunderstanding, and more understanding and kindness. I also hope that medical technology will be more developed in the future, so that these special patients can get better treatment and return to ordinary people’s lives.

[References]

[1]Agharbi FZ. Epidermodysplasie verruciforme: à propos d’un cas [Epidermodysplasia verruciformis: about a case]. Pan Afr Med J. 2018 May 29; 30:78. French. doi: 10.11604/pamj.2018.30.78.16058. PMID: 30344862; PMCID: PMC6191268.

Yang Hui, Liu Wan, Chang Jianmin. Verrucous epidermal dysplasia [J]. Journal of Clinical Dermatology, 2015:13-14.

Wang Zehua, Li Hongyu, Qu Jing, Zhang Weiqi, Liu Guanghui. Pathogenesis and intervention methods of human premature senility [J]. Progress in biochemistry and biophysics, 2018,45(09):926-934.

[4] Erythrocyte Disease (Anemia) Group, Hematology Branch, Chinese Medical Association. Expert Consensus on Diagnosis and Treatment of Porphyrin Disease in China (2020) [J]. Chinese Medical Journal, 2020,100 (14): 1051-1056.

[5]Pavone P, Praticò AD, Falsaperla R, Ruggieri M, Zollino M, Corsello G, Neri G. Congenital generalized hypertrichosis: the skin as a clue to complex malformation syndromes. Ital J Pediatr. 2015 Aug 5; 41:55. doi: 10.1186/s13052-015-0161-3. PMID: 26242548; PMCID: PMC4526284.

[6]Sun M, Li N, Dong W, Chen Z, Liu Q, Xu Y, He G, Shi Y, Li X, Hao J, Luo Y, Shang D, Lv D, Ma F, Zhang D, Hua R, Lu C, Wen Y, Cao L, Irvine AD, McLean WH, Dong Q, Wang MR, Yu J, He L, Lo WH, Zhang X. Copy-number mutations on chromosome 17q24.2-q24.3 in congenital generalized hypertrichosis terminalis with or without gingival hyperplasia. Am J Hum Genet. 2009 Jun; 84(6):807-13. doi: 10.1016/j.ajhg.2009.04.018. Epub 2009 May 21. PMID: 19463983; PMCID: PMC2694973.

[disclaimer]

The data in this article was updated on May 14th, 2021.

It was originally written by Professor Yang Xichuan, a dermatologist, aiming at popularizing science for readers.

Popular science content can not replace doctors’ diagnosis and treatment opinions, and is for reference only.

If you have skin problems, please consult a doctor in time.

Some pictures are from the Internet. If there is any infringement, please contact to delete them.

Cover image source: blurrr

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　　China Overseas Chinese Network March 1st Issue: From March, these new regulations will affect the lives of overseas Chinese!

　　The season has passed the rain, and Miss Chun’s footsteps are getting closer and closer. Looking around, maybe it’s still "the grass looks close but there is nothing", but I believe that "the branches of red apricots are full of spring" is not far away.

　　A year’s plan starts with spring. Xiaoqiao first wishes everyone a good start, a good step and a full and wonderful 2019.

　　In March, what major events are about to happen? What new rules will affect the lives of overseas Chinese? Xiao Qiao will show you below.

　　March event: the two sessions of the National People’s Congress are about to start.

　　The second session of the 13th National People’s Congress and the second session of the 13th National Committee of the Chinese People’s Political Consultative Conference will be held in Beijing on March 5 and March 3, 2019, respectively.

　　At that time, NPC deputies and CPPCC members from all walks of life will shoulder great trust and discuss the country. Overseas Chinese from all over the world will also come to Beijing, the capital, to give voice to the overseas Chinese community at the meeting. (detailed)

　　Overseas Chinese concern

　　In 2019, the joint enrollment of Jida and Huada was launched.

　　The Admissions Office of Jinan University recently announced the registration instructions for the 2019 Guangzhou entrance examination for students from Hong Kong, Macau, Taiwan Province, overseas Chinese, Chinese and other foreign countries jointly enrolled by Jinan University and Huaqiao University.

　　Eligible candidates can make online name prediction from March 1st to March 29th.

　　112 colleges and universities in the Mainland will enroll Hong Kong students online in advance from March.

　　According to the Hong Kong Business Daily, the Hong Kong Education Bureau announced on the 25th that 112 institutions of higher learning in the Mainland participating in the enrollment plan for Hong Kong students without examination will accept online pre-registration from March 1st. Well-known art schools, such as the Central Conservatory of Music, the Central Academy of Drama and the Central Academy of Fine Arts, have been added, and famous institutions such as Peking University, Tsinghua University and Fudan University are also on the list.

　　According to the enrollment procedure in 2019, colleges and universities can arrange interviews according to candidates’ application materials, and announce the admission list online in late July.

　　China and Algeria will exempt each other from diplomatic visas.

　　After the entry into force of the agreement, China citizens with valid diplomatic and official passports from China will be exempted from visas and can stay for no more than 90 days every 180 days from the date of entry.

　　Those who intend to enter Algeria for work, study, settlement, news reporting and other activities that require the prior approval of the competent authorities of the country should complete the relevant visas before entering Algeria.

　　Thailand will launch e-visa

　　On March 1st, Thailand’s e-visa system will be extended to the consulates general of Thailand in various cities in China, and China citizens who need to travel to Thailand can fill in and submit visa applications online at any time and place through the Internet.

　　After obtaining the online examination and approval from the Immigration Bureau of Thailand, tourists can quickly enter the country from the electronic visa-on-arrival channel with their passports.

　　New domestic regulations

　　Tax reduction of rare disease drugs

　　In order to encourage the development of the pharmaceutical industry with rare diseases and reduce the cost of patients’ medication, the Ministry of Finance, the General Administration of Customs, the State Administration of Taxation and the Food and Drug Administration jointly issued a notice to reduce the value-added tax on the first batch of 21 drugs with rare diseases and 4 APIs by 3% from March 1.

　　New pilot of vocational education reform

　　The Ministry of Education plans to launch a pilot system of "academic certificate+vocational skill level certificate" in vocational colleges and applied undergraduate colleges from March, and encourage students to actively obtain various vocational skill level certificates while obtaining academic certificates; Students choose to participate in vocational skill level certificate training and assessment independently, which is not a restrictive condition for graduation.

　　Activate the new business license

　　The General Administration of Market Supervision issued a notice to activate the new business license from March 1st. The new license maintains the eight formats of the original license; Increase the function of two-dimensional code to facilitate all sectors of society to understand the situation of market players; For the market subject who has received the new paper business license, it is necessary to simultaneously generate the new electronic business license and store it in the electronic business license database.

　　It is more convenient to tax and invoice.

　　In order to optimize the business environment, the State Administration of Taxation decided to further expand the pilot scope of issuing special VAT invoices by small-scale taxpayers from March 1, and to include leasing and business services, scientific research and technical services, residents’ services, repairs and other services. At the same time, the scope of taxpayers who cancel the VAT invoice certification will be extended to all general taxpayers.

　　Implementation of that new patent agency regulation

　　The revised Patent Agency Regulations will come into force on March 1st. The regulations optimize the business environment and relax the access conditions for patent agents and agencies; Improve the way of inspection and supervision, strengthen the supervision of patent agency activities during and after the event: increase the convenience and benefit of the people, and improve the efficiency of patent services.

　　Local scanning

　　Shanghai: Unsold parking spaces in residential areas cannot be sold without rent.

　　The revised "Shanghai Residential Property Management Regulations" will be implemented on March 1. The new regulations make it clear that the parking spaces that have not been sold by the construction unit should be leased to the owners and users to park their vehicles, and they should not refuse to rent them on the grounds that they are only for sale but not for rent; Encourage owners and surrounding units of residential quarters to share parking resources through consultation.

　　Sichuan: Medical insurance for urban workers can be shared with their families.

　　From March 1st, Sichuan Province will implement the new policy of personal account for urban workers’ basic medical insurance, and the personal account funds will be used by their spouses, parents and children of both husband and wife in addition to the employees’ own use, so as to realize the mutual help of family members.

　　Guangdong: Motor vehicles will be restricted in foggy days.

　　The Regulations on the Prevention and Control of Air Pollution in Guangdong Province came into effect on March 1st. The regulations make it clear that some motor vehicles can be restricted when facing heavy polluted weather; The municipal government at or above the prefecture level may, according to the needs of air pollution prevention and control, take measures such as restricting traffic to eliminate high-emission vehicles.

　　Macau: It is forbidden to carry a 30cm selfie stick with you at the airport.

　　From March 1st, Macau International Airport will not allow passengers to bring the following kinds or quantities of articles into the cabin or airport security restricted area in the form of carry-on or hand luggage, including baseball/softball bats and cricket bats, fishing rods, cameras over 30cm after being folded, video tripods, monopods and selfie sticks.

　　These days are worth noting.

　　March 5: Zhou Enlai’s birthday anniversary

　　March 5th: "Learning from Comrade Lei Feng" Memorial Day

　　March 8: International Women’s Day

　　March 12th: the anniversary of Sun Yat-sen’s death

　　March 12th: Arbor Day in China.

　　March 15th: International Consumer Rights Day

　　March 21st: International Day for the Elimination of Racial Discrimination

　　March 21st: World Sleep Day

　　(Source: China Overseas Chinese Network official WeChat, Author: Ran Wenjuan, ID: qiaowangzhongguo)

Dr. Guan Kang Kang You from the Department of Nuclear Medicine talks about thyroid gland.

1. What is pepsinogen?

Pepsinogen (PG) is the precursor of pepsin. According to its biochemical properties and immunogenicity, it can be divided into two subgroups. The immunogenicity of 1~5 components is the same, and it is called Pepsinogen I (PG I), which is mainly secreted by the main cells of gastric fundus gland and mucus neck cells. Components 6 and 7 are called pepsinogen Ⅱ(PGⅡ), which can be secreted by the main cells and mucus neck cells of gastric fundus gland, and also produced by mucus neck cells of pyloric gland of cardiac gland and gastric antrum and upper duodenum.

Usually, about 1% PG enters the blood circulation through the capillary of gastric mucosa, and the PG entering the blood circulation is very stable in the blood. Serum PG ⅰ and PG ⅱ reflect the number of glands and cells in gastric mucosa, and indirectly reflect the secretory function of different parts of gastric mucosa. When pathological changes occur in gastric mucosa, the content of serum PG also changes. Therefore, monitoring the concentration of PG in serum can be used as a means to monitor the status of gastric mucosa.

Detection of pepsinogen (PG), an early warning indicator of gastric cancer

1. Chronic atrophic gastritis is an important "transitional event" in gastric mucosa canceration.

Gastric cancer is one of the common malignant tumors in China, and its mortality ranks first among all kinds of malignant tumors. Its early diagnosis and early treatment have become the only way to improve the quality of life of patients and reduce the mortality. At present, the main methods for diagnosing gastric cancer are fiberoptic gastroscopy and upper gastrointestinal radiography, among which gastroscopy is called the "gold standard" for diagnosing gastric cancer.

At present, it is believed that partial atrophy can be reversed, and once it enters intestinal metaplasia, it is difficult to reverse it. Therefore, there is an urgent need for a tool that can keenly detect the atrophy of gastric mucosa. At this time, the detection of pepsinogen plays a powerful role.

When the gastric fundus gland atrophied, the number of main cells decreased and the level of PG ⅰ decreased. However, because there are more cells secreting PG ⅱ, PG ⅱ can still maintain a high level at this time, and the ratio of PG ⅰ to PG ⅱ decreased significantly. When atrophic gastritis is accompanied by intestinal metaplasia and gastric antrum gland extends to the stomach body, and pseudopyloric metaplasia of gastric fundus gland occurs, the level of PG ⅱ increases more, and the ratio of PG ⅰ to PG ⅱ decreases further. Therefore, the decrease of PG ⅰ level is a reliable sign of gastric fundus gland mucosa atrophy, and PG ⅰ/PG ⅱ profile reflects the degree of gastric fundus gland mucosa atrophy.

2. Helicobacter pylori infection is the initiating factor for the development of gastric cancer.

The occurrence of gastric cancer is the result of multiple factors. The multi-step hypothesis of gastric cancer, that is, from chronic non-atrophic gastritis (formerly known as chronic superficial gastritis) → atrophic gastritis → intestinal metaplasia → intraepithelial neoplasia (formerly known as dysplasia) → gastric cancer, has been generally accepted. Helicobacter pylori (Hp) infection has become the most important initiating factor, and Hp infection has been recognized as an independent risk factor for gastric cancer.

Therefore, active detection of Hp has become one of the important measures to prevent and treat gastric cancer. Hp detection is mainly divided into invasive and non-invasive methods. For Hp-positive infected people, the major guidelines have reached a consensus that Hp infection-related gastritis is an infectious disease and it is recommended to eradicate it.

Hp infection can also significantly affect the serum PG level. At the beginning, PG ⅰ and PG ⅱ both increased, and the increase of PG ⅱ was faster, then PG ⅰ/PG ⅱ decreased, and the larger the Hp infection focus, the greater the decrease of PG ⅰ/PG ⅱ. However, the results of pepsinogen test are lack of specificity, and special Hp test is still needed to judge whether Hp is infected or not.

Third, pepsinogen Ⅰ(PGⅠ),

The results of pepsinogen Ⅱ(PGⅡ) were analyzed as follows:

Four, "pepsinogen" test results misunderstanding:

Myth # 1: If only PG ⅰ is measured during physical examination, nearly 70% of the results are in the range of 40~70ng/mL, which seems to be lower than 70ng/mL on the surface, and gastric atrophy is suspected, but the results are difficult to explain because PG ⅱ and ratio are not measured. When PGⅡ is retested, the ratio of more than 90% is greater than 3. This kind of situation is due to the high incidence of chronic superficial gastritis in China population, which belongs to normal physiological gastric acid secretion insufficiency.

Myth 2: PG-positive means "stomach cancer theory": positive means people at high risk of stomach cancer. PG project is a simple screening project for gastric cancer in the early stage of physical examination, replacing X-ray and ultrasonic screening for gastric cancer. The main significance lies not in diagnosis but in early detection and prevention. Normal people are 15%PG positive, and those with PG positive have a high risk of developing gastric cancer, and the early detection rate of gastric cancer is 1%~2%.

Myth # 3: Pay attention to the change of reference range values of PG ⅰ and PG ⅱ, but not the ratio. Because the secretion of PG ⅰ in gastric mucosa changes greatly (above 70~800ng/mL) under the attack of inflammation, the secretion of PG ⅱ is relatively constant. When comparative value > 3, the degree of PG ⅰ increase can only be combined with clinical analysis to determine the type of gastric diseases. When comparative value < 3, it is suggested that further in-depth endoscopy or pathological sampling should be taken to confirm and warn the high risk of early gastric cancer, and follow-up monitoring should be carried out in the last five years. The incidence of gastric cancer was 2% in PG-positive patients who had no gastric cancer in the same year and in the following five years.

Five, Japan’s experience for reference ("ABC" method+endoscopic screening)

Our neighbor Japan, as a country with high incidence of gastric cancer, has done a very good job in early cancer screening. Their screening strategy for early cancer firmly grasps the two controllable factors of Hp infection and whether gastric fundus gland atrophy occurs.

The Kyoto Consensus of Japan made the following recommendations for the national early cancer screening strategy: first, for Hp infection, the Kyoto Consensus emphasized "shoot to kill", and after everyone sterilized and eradicated Hp, PG was evaluated. The ratio of PG ⅰ/PG ⅱ is ≤3.0, which is regarded as the critical diagnostic value of atrophic gastritis, and as the screening standard of high-risk population of gastric cancer.

Vi. A Long Way to Go-Strategies for Early Cancer Screening in China;

China has a large population base and the incidence of gastric cancer remains high, so it is imperative to find a simple, accurate and effective screening method for gastric cancer. In 2017, the China Consensus on Chronic Gastritis highly affirmed the value of PG, and the guidelines gave the following recommendations: The detection of serum pepsinogen (PG) ⅰ and ⅱ and gastrin -17 may help to judge whether there is gastric mucosal atrophy and its degree. Detection of serum PG ⅰ, PG ⅱ, PG ⅰ/PG ⅱ ratio combined with anti-Hp antibody is helpful for risk stratification management.

The Expert Consensus on Early Gastric Cancer Screening Process in China, published at the end of 2017, not only affirmed the value of serum PG, but also put forward a new gastric cancer screening scoring system, in which the elderly, male, Hp antibody positive, low pepsinogen ratio (PGR) and high serum 17(gastrin-17 (G-17) level are high risk factors for gastric cancer.

Among them, G-17 is a new item in China Guide. G-17 is an amidated gastrin synthesized and secreted by G cells in gastric antrum. Its main physiological function is to stimulate gastric acid secretion and promote the proliferation and differentiation of gastric mucosal cells. G-17 is one of the sensitive indexes to reflect the endocrine function of gastric antrum, which can indicate the atrophy of gastric antrum mucosa or whether there is abnormal proliferation. G-17 itself can also promote the occurrence and development of gastric cancer. When the serum G-17 level rises, it may indicate the risk of gastric cancer.

In addition, different from the Kyoto consensus, the consensus in China put forward the critical value of serological detection for the first time, that is, when PGR<3.89 and G-17> 1.50pmol/L, the risk of gastric cancer increased significantly. The critical value of PGR defined by Kyoto Consensus is ≤3.

According to the score, the guide divides the population into three groups: low risk, medium risk and high risk, and gives the screening strategy.

At the same time, however, we should also see the shortcomings of the China guidelines. The screening population is over 40 years old, and there are other risk factors such as high incidence area of gastric cancer, Hp infection, previous precancerous diseases of gastric cancer, first-degree relatives of gastric cancer patients, diet and so on. However, at present, the onset age of gastric cancer is getting earlier and earlier, and I believe it will definitely enter prospecting stage in the future.

To sum up, serum PG combined with Hp detection is helpful to evaluate the risk of gastric cancer, and can be used as a routine screening method for gastric cancer for ordinary people. However, it cannot replace gastroscopy, and gastroscopy is still strongly recommended for high-risk groups.

Original title: Clinical Significance of Detection of Pepsinogen (PG)

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Vision china diagram

News from The Paper, Hebei, one of Gree Electric’s important markets, has suffered an unexpected change just as air-conditioning enterprises are preparing for the new freezing year.

It is reported that Hebei Xinxing Gree Electric Sales Co., Ltd. (Hebei Gree), a distributor in Gree Electric, issued a notice on August 18th, saying that on August 16th, Gree Electric suddenly stopped the delivery of goods to Hebei Gree, and asked the distributors who had invested money to plan and pick up the goods as soon as possible.

Just four days after Gree Electric cut off the supply of Gree in Hebei, on August 20th, Xu Zifa, the chairman of Hebei Xinxing Gree Electric Sales Co., Ltd., hosted a banquet for the mainstream distributors in Shijiazhuang five-star hotel, and announced at the meeting that he would quit the operation of Gree from today! At the same time, he promised to give everyone a reassurance, and the dealer’s payment, rebate and anwei fee will be cashed for everyone.

According to a reporter from The Paper who learned from an insider, the details of "Moutai that was drunk for 15 years that night, and 100,000 cash was distributed to 10 people at each table" were true. Xu Zifa also thanked the dealer for his support for so many years.

On August 23rd, a reporter from The Paper called Hebei Gree, and the staff who answered the phone said "there is no obligation to answer whether the company will continue to sell Gree air conditioners" and "if you want to buy Gree air conditioners, the market is everywhere".

Gree Electric also chose to play it cool. As of press time in The Paper, Gree Electric has not responded positively to this matter.

However, The Paper reporter learned from a number of people in the home appliance industry that Gree Electric really fell out with Hebei Gree. Next, Gree Electric will re-establish distribution channels in Hebei.

Some media reported that after Gree stopped supplying to the general distributor in Hebei, Gree Zhuhai Headquarters sent a 50-member marketing team to Hebei, bypassing the original general distribution of Gree in Hebei and contacting local agents. The Paper reporter also learned from insiders that the situation is basically true.

The strength of Hebei Gree should not be underestimated.

Hebei Xinxing Gree Electric Sales Co., Ltd. is one of the most powerful distributors in Gree Electric. Jinghai Internet Technology Development Co., Ltd. (Jinghai Internet), which was established by Hebei Gree and more than a dozen Gree Electric distributors, is an important shareholder of Gree Electric. As of the first quarter of this year, Jinghai Internet holds 8.34% of the shares of Gree Electric, ranking the third largest shareholder.

Tianyancha information shows that Hebei Gree indirectly holds 28% of the shareholders of Jinghai Internet and is also the largest shareholder of Jinghai Internet.

However, on June 24th this year, Gree Electric announced that it had received the Notice of Share Reduction from Jinghai Internet, a shareholder holding more than 5% of the shares. On June 24th, 2022, Jinghai Internet reduced its shareholding by 110,219,217 shares, accounting for 1.86% of the total share capital of Gree Electric, and cashed in 3.5 billion yuan. After the reduction, the shareholding ratio of Jinghai Internet decreased to 6.47%.

More importantly, as a major distributor in Gree Electric, Xu Zifa is also an investor in Philips Air Conditioning, which may also be one of the reasons for the deadlock between the two sides.

On August 9th this year, at the new product launch conference held by Philips Air Conditioning, Huang Hui, the former CEO of Gree Electric, appeared as the chairman of Philips Air Conditioning, Vinfom Hu, the assistant to the former president of Gree Electric, became the president of Philips Air Conditioning, and Xu Zifa attended the meeting as the shareholder representative of Philips Air Conditioning.

Gree turned into a competitor of Gree, which obviously angered Gree.

Liu Buchen, a senior home appliance observer, said in an interview with a reporter from The Paper that Gree Electric must be very dissatisfied with this practice of Hebei Gree. Before that, Gree Electric asked the dealer to choose one, and if he wanted to represent Gree, he could not represent Philips.

"Hebei Gree has both active and passive factors in doing so. Passive factors Gree Electric has promoted channel transformation in recent years, and the proportion of online sales has become higher and higher, which has affected the interests of traditional dealers and forced them to seek new ways out; However, investing in Philips is definitely the initiative of Hebei Gree. Considering so many years of experience and resources, I will try Philips air conditioning. " Liu Buchen said that he is not optimistic about the future prospects of Philips Air Conditioning and will not pose a threat to Gree.

However, Liu Buchen believes that it will take time for Gree to change the Hebei channel and find a suitable candidate, which may have a negative impact on Gree’s local sales.

However, the Hebei dealer incident did not bring much pressure to Gree Electric’s share price. On August 23rd, Gree Electric closed at 30.23 yuan, a decrease of 0.85%. The total market value of Gree Electric is 170.2 billion yuan.

Original title: Drink Maotai and discover gold! Xu Zifa took the lead in Hebei dealers and announced that he would quit Gree and went to Philips.

[Original Truck House] For the 8X4, many friends think that the horsepower above 400 is a bit wasteful, but in the transportation fields such as Lutong and cold chain, the high-horsepower models are growing. The warehouse-grid container has the advantages of large loading capacity and convenient and flexible loading and unloading, and has always been a "generalist" in the freight field. Therefore, in this issue, Xiaobian found four 8×4-drive warehouse trucks with horsepower above 400. Let’s take a look at what sparks can be caused by high horsepower and warehouse boxes, and also provide reference for card friends to choose cars.

"Big Hook 7" is a domestic benchmark in the hearts of many card friends, and the new trucks naturally bring all the excellent qualities they have. First of all, in terms of appearance, this J7 truck is very eye-catching, using a green color scheme, and it also reveals some vitality in its fortitude. China Net adopts a multi-layer point air intake grille with V-shaped decoration, which is very layered and gives people the feeling of strong abdominal muscles, and its appearance is quite amazing.

In terms of power, J7 truck is equipped with CA6DM2-46E6, with a displacement of 11L, a maximum power of 460 HP and a peak torque of 2300N·m, which can output the maximum torque at 1000-1400rpm.

Matching with the engine is the liberated 12-speed manual, the model is CA12TA230M3, and the direct gear design is adopted. The head gear ratio is 15.575, and the highest gear ratio is 1. This is a double countershaft all-aluminum case gearbox developed to meet the needs of light weight, large torque and long life in the market. The service life of the gearbox B10 is 1.5 million kilometers, and the oil change mileage is 100,000 kilometers.

The rear axle of J7 truck is a lightweight 440 rear axle with a speed ratio of 2.867, and the front disc rear wedge brake is adopted.

In terms of chassis configuration, J7 truck adopts the technology of few leaf springs, with two leaf springs on the front axle and four leaf springs on the rear suspension. This technology not only reduces the center of gravity of the whole vehicle, but also increases the cargo capacity by about 2%. The technology of less leaf spring combined with front axle shock absorber makes the driving quality of J7 8×4 truck closer to that of family car.

J7 truck uses brand 12R22.5 size 18-level tubeless and steel rims. The steering wheel is also equipped with maintenance-free oil lubrication wheel end.

The length of the vehicle is 12 meters, the width of the body is 2.55 meters and the height of the body is nearly 4 meters. The size of the car’s matching barn-type jacket is 9.5 meters long and 2.46 meters wide, and the container is also green, fresh and refined. From this angle, we can also see the parking air conditioner on the roof.

The J7 8×4 truck is also equipped with an autonomous air-driven urea system, which has the advantages of simple structure, low failure rate and difficult crystallization.

The cab is naturally the performance of the flagship tractor. With a nearly flat floor, adults with a height of 180cm still have great wealth standing in the cab head space. The four-position steering wheel has multi-function buttons, and the left and right sides can control multimedia and cruise control functions respectively. The main driver’s seat is equipped with an airbag shock-absorbing seat, which has ventilation and heating functions and has a right armrest. The seat belt is also designed in one piece.

The berth space is very spacious, measured at the widest point is about 82cm, the narrowest point is about 76cm, and the thickness of the mattress is 10cm. The real car and the cab that the card friends have spent a lot of time arranging are very western.

The performance of Daguo 7-year-old truck is quite balanced, and it has a high reputation in the eyes of card friends with the good reputation accumulated by tractors. This set of independent power chain configuration, combined with the unique pneumatic urea system, Bridgestone tires, parking air conditioning and rich safety and comfort configuration, makes the J7 truck competitive.

Before the X6000 truck, the X50008X4 trucks are urgent to hit the high-end cargo market.It uses a U-shaped mesh, and the wavy embellishment and chrome trim of the mesh make the trolley look exquisite and resolute. Hawkeye vertical headlights are very energetic, and the light group has LED daytime running and lens, which ensures the paving effect and has less influence on the oncoming traffic.

In terms of power, the X5000 truck is equipped with a 10.5L displacement diesel engine, with a maximum output of 460 HP and a peak torque of 2100 N m. The engine is matched with a 16-speed automatic gearbox.

The rear axle is a 10.5-ton rear axle with a speed ratio of 3.7. Through the calculation of the speed calculator of the truck house, when the engine of the car is 1100-1300 rpm, the gearbox adopts the highest gear, and the speed can reach 75-89km/h, and LaLutong is also very powerful.

Chassis configuration, X5000′ sThe 8X4 truck is equipped withThe 700L aluminum fuel tank can also be equipped with 700+300L double fuel tanks, which is very sufficient for Lutong transportation.

X5000 The dimensions of the 8X4 stockyard truck are 12m long, 2.55m wide and 3.98m high. The size of the matching barn top is 9.5 meters long and 2.45 meters wide.

When I came to the X5000 cab, the texture of the three-color design of black, off-white and logs was in place, and the central control area was designed in layers, with distinct layers. X5000 also uses the flat-bottomed steering wheel that is common in sports passenger cars, which not only models sports, but also makes it easier for card friends to enter and leave the sleeper area in actual use. The gear shifting mechanism adopts the design of holding gear. Due to the lack of manual gear handle, the whole cab looks simple and generous. The central control screen also provides navigation, voice control, air conditioning, Bluetooth, mobile phone interconnection and other functions, which are practical and easy to use.

The airbag shock-absorbing seat equipped with this car is also from Grammer brand, and the adjustment options are very rich. The lumbar back support can be adjusted separately, and the seat ventilation, one-button inflation and deflation, cushion pitch angle and so on are very convenient for the driver to operate.

The sleeper area is also considerable. The width of the sleeper of the X5000 truck is about 90cm, and there is a USB interface and lighting at the bedside. There are curtains between the rear window and the cab to ensure the privacy of the driver when he is resting, which is very humanized.

X5000′ s classic gold power chain of Weichai+Fast+Hand has a good reputation among card friends. With a cab full of texture and a wide berth, the configuration can not be said to be unsatisfactory. Will you give priority to it when you run the green pass transportation?

The next appearance is very eye-catching. It comes from A5W 8X4 warehouse truck. The general appearance of the mecha is very sci-fi, with sharp lines and a sharp-edged feeling. I think this appearance will definitely be favored by young friends. After all, who doesn’t want to drive a truck with a cool appearance?

Truck users have always pursued high timeliness, and have higher requirements for bearing capacity and comfort. However, in the past, tractors were far ahead of contemporary trucks, and the arrival of A5W flagship trucks also made truck users feel full of concern.

In terms of power, A5W truck is equipped with X12NB490 inline six-cylinder diesel engine, with a displacement of 11.8L, a maximum output of 490 horsepower and a peak torque of 2300N·m, which can output the maximum torque at 1000-1400rpm. With such a high horsepower engine on the truck, it is very adaptable to the pursuit of timeliness and complex road conditions.

The gearbox matched with the engine is 12TX2420TD, which is a 12-speed AMT gearbox with direct gear design and the highest gear ratio of 1. The A5W with AMT gearbox has brought more comfortable and relaxed driving experience to the card friends, and running Green Link can save a lot of energy.

The speed ratio of the rear axle of A5W truck is 2.846. It can be calculated by the speed calculator of Truck House that the speed of the car can reach 69-97Km/h in the economic speed range of 1000-1400rpm when the engine adopts the highest gear, which makes it run very fast, which gives it an advantage in speed. This A5W has a very good performance for the transportation scenes such as Lutong, which pursues timeliness.

In terms of chassis configuration, A5W suspension adopts leaf spring suspension, and the number of leaf springs of 3+3+12 reduces the dead weight as much as possible under the condition of ensuring the bearing capacity. Wan Li SFR03 tire is used as the tire, with the specification of 12R22.5. This tire focuses on comprehensive working conditions and wear resistance. Moreover, the aluminum alloy rim is adopted at any cost, which can further reduce the self-weight. Its steering is also equipped with Kangmai visual oil lubrication wheel end, which is worry-free and durable.

In terms of fuel tank, A5W is equipped with an 800L fuel tank, which can bring about 2500 kilometers of endurance for the car. As far as single fuel tank is concerned, this volume ranks among the top models in this inventory.

A5W’s 8X4 stockyard truck is 12m long, 2.55m wide and 3.99m high. On the top, the container of this A5W truck is 9.6m in length and 2.46m in width.

The cab design of A5W is very close to that of flagship tractors K7 and V7 made by Juegel, with excellent texture and ergonomics. There is a large area of leather covering above the center console, and there is even a brushed aluminum decorative board on the air outlet of the air conditioner. The center console is tilted towards the driver as a whole, and all the buttons are within reach.

A5W with flat floor cab is very rich in space, and the bar is far away from the center console, which is very convenient for the driver’s seat to enter and exit. The bar of the car follows the seat, and no matter how the seat moves, the bar is in the most convenient place. And on the right side of the air brake, a kettle rack with a fixed belt is prepared intimately, which is convenient for card friends to store boiled water.

The sleeper area A5W is even wider, with a width of about 1 meter, which ranks among the top models in this inventory. And both ends of the sleeper are also designed with openable windows, which is very convenient for ventilation. Near the rear of the cab, there are also mesh bags and shortcut buttons, which can control the window lifting, interior lighting and so on.

High-horsepower engine, flat-floor cab, AMT automatic transmission and super-wide sleeper, which once appeared in the high-end configuration of tractors, are now equipped on A5W trucks, so that truck riders can also have on-call power, carefree driving experience, comfortable and rich configuration.

The 8X4 truck is a model based on the scenes of high-efficiency green pass, livestock transportation and logistics distribution, and inherits the good reputation of EST in high-end tractors, which is efficient, fuel-efficient and reliable.

The car is equipped with Fukang’s 430 HP engine, which is an in-line six-cylinder diesel engine with a displacement of 11.8L L. The maximum horsepower is 430 HP, the peak torque is 2200N·m, and the maximum torque speed is 1000-1400rpm.

Matching the engine is the Fast 12JSDX240TA gearbox, the shell is made of aluminum alloy, and the overdrive gear is designed, with the head gear ratio of 12.1 and the highest gear ratio of 0.78. The rear axle speed ratio is 3.7.

This EST All the 8X4 trucks are equipped with Jiaan brand tires with specifications of 12.00R2016pr..The steering wheel is also equipped with Kangmai’s long-term maintenance oil to lubricate the wheel end, and the longest oil change cycle is 500,000 kilometers, which can save maintenance costs and further improve the overall attendance rate.

Through the calculation of the speed calculator of the truck house, we can draw that the engine speed of the truck is within the economic speed range, and the speed can reach 76-89km/h when the gearbox adopts the highest gear, which shows the advantages of high efficiency.

In terms of chassis configuration, the suspension of EST 8X4 truck, which focuses on the standard load transport scene, adopts the design of 2+2+4 small leaf springs and straight-through girders, which ensures the bearing capacity and achieves the effect of lightweight body.

The car is equipped with an aluminum alloy fuel tank with a volume of 600L, which is sufficient for medium and long-distance transportation. In terms of body size, the whole length of EST 8X4 truck is 12m, the body width is 2.55m and the body height is 3.95m.. The matching top size of the car is 9.56 meters long and 2.45 meters wide.

EST The interior of the 8X4 truck is the same as that of the EST tractor, and the whole center console is designed in an embracing way, with the middle protruding towards the cab. This makes the function keys near the driver’s side very easy to operate. In the middle of the center console is an air outlet, a power supply interface and a cigarette lighter interface, and the storage island below also provides rich storage spaces such as cup holders, storage compartments and drawers.

The steering wheel of EST truck adopts four-position design, with multi-function buttons and leather package. The whole steering wheel has a very round shape and a thick grip.

The seat of EST truck adopts CVG brand airbag shock-absorbing seat, which is covered with leather and has excellent touch. It can provide the functions of waist and back support adjustment, cushion pitch angle, shock absorption and damping adjustment, rapid inflation and deflation, etc. The seat belt is also an integrated design, which can always follow the driver’s shoulder, which is not easy to wear and is safer.

Fukang truck is equipped with gold transmission combination, lightweight standard-load chassis configuration, and long-term tanker-changing end configuration. This Ou Man EST light truck has made many targeted optimizations to improve attendance and timeliness, so as to meet the needs of market segment users more accurately.

● 　Editor’s note:

In recent years, the progress of domestic trucks in power is obvious to all, and many card friends who pursue high-efficiency transportation begin to turn their attention to high-horsepower models. Even though high-horsepower trucks have advantages that other vehicles can’t catch up with in power, there is no need to blindly pursue high horsepower when returning to the car selection, but it should be determined according to their specific car scenes. Scenes such as green link, cold chain and complex road conditions are the places where high-powered trucks come into play. (Text/Kong Xiangyu Figure/Truck House)

　　CCTV News:According to the website of China Banking and Insurance Regulatory Commission, China, recently, the Consumer Protection Bureau of China Banking and Insurance Regulatory Commission, China issued the Notice on the Complaints about Insurance Consumption in the Second Quarter of 2022 (No.11 Notice of 2022, hereinafter referred to as the Notice), which informed the complaints about insurance consumption received and transmitted by China Banking and Insurance Regulatory Commission and its dispatched offices.

　　According to the Circular, China Banking and Insurance Regulatory Commission and its agencies received and forwarded 28,554 complaints about insurance consumption in the second quarter. Among them, 10051 property insurance companies were involved, accounting for 35.20% of the total complaints; There were 18,503 life insurance companies, accounting for 64.80% of the total complaints. The number of complaints from PICC P&C ranks first among property insurance companies. The number of complaints in Ping An Life Insurance Company of China ranks first among life insurance companies.

　　According to the Circular, in the second quarter of 2022, the median number of complaints about 100 million yuan premium of property insurance companies was 3.58 pieces/100 million yuan, and the median number of complaints about 10,000 policies was 0.36 pieces/10,000 pieces; The median number of complaints about 100 million yuan premium of life insurance companies is 1.78/100 million yuan, the median number of complaints about 10,000 policies is 0.25/10,000, and the median number of complaints about 10,000 people is 0.08/10,000. Zhonghui Mutual Insurance ranks first among property insurance companies in terms of the complaints about the 100 million yuan premium. The number of complaints about 10,000 policies of Jiulong Property Insurance and Zhonghui Mutual Insurance ranks in the top two among property insurance companies. Fosun United Health ranks first among life insurance companies in terms of complaints about 100 million yuan premium, complaints about 10,000 policies and complaints about 10,000 people.

　　According to the Circular, in the second quarter of 2022, there were 7,808 complaints about claims disputes involving property insurance companies, accounting for 77.68% of the total complaints of property insurance companies; There were 822 complaints about sales disputes, accounting for 8.18%. Zhonghui Mutual Insurance, PICC P&C Insurance and Zhongan Online P&C Insurance rank among the top three property insurance companies. PICC P&C Insurance and Ping An P&C Insurance rank in the top two among property insurance companies.

　　In the second quarter of 2022, property insurance companies filed 4324 complaints about motor vehicle insurance disputes, accounting for 43.02% of the total complaints of property insurance companies; There were 2,434 complaints about other insurance disputes involving property insurance such as COVID-19 epidemic isolation insurance, accounting for 24.22%. PICC P&C ranked first among property insurance companies in the number of complaints about motor vehicle insurance disputes. Zhonghui Mutual Insurance and Zhongan Online Property Insurance are among the top two property insurance companies in terms of complaints about property insurance related to COVID-19 epidemic isolation and other insurance disputes.

　　According to the Circular, in the second quarter of 2022, there were 9,613 complaints about sales disputes from life insurance companies, accounting for 51.95% of the total complaints from life insurance companies. There were 5011 complaints about surrender disputes, accounting for 27.08%. The number of complaints about sales disputes and surrender disputes in Ping An Life Insurance Company of China ranks first among life insurance companies.

　　In the second quarter of 2022, there were 8101 complaints about ordinary life insurance disputes from life insurance companies, accounting for 43.78% of the total complaints from life insurance companies; There were 4182 complaints about sickness insurance disputes, accounting for 22.60%. The number of complaints about ordinary life insurance disputes in Ping An Life Insurance Company of China ranks first among life insurance companies. Ping An Life Insurance Company of China and Xinhua Life Insurance ranked the top two in terms of complaints about sickness insurance disputes among life insurance companies.

▲ At a nucleic acid testing point in Sanjianfang area, a volunteer recruitment applet code was posted behind the staff. Photo courtesy of respondents

▲ At a nucleic acid testing point in Sanjianfang area, a young volunteer is instructing children how to disinfect. Photo courtesy of respondents

▲ At a nucleic acid testing point in Sanjianfang area, the staff is instructing a young man how to scan the code and register as a volunteer. Photo courtesy of respondents

　　CCTV News:In order to improve people’s attention to chronic kidney disease (CKD), the International Society of Nephrology (ISN) and the International Foundation for Nephrology (IFKF) jointly designated the second Thursday of March every year as "world kidney day". March 14th, 2019 is the 14th world kidney day, and this year’s theme is "Kidney Health for All".

　　On March 17th, more than 200 leaders, nephrologists and medical staff, including Yang Min, Vice President of Chinese Medical Doctor Association, Jin Dapeng, Chairman of Nephrology Branch of Beijing Medical Association, Chairman of Nephrology Branch of Chinese Medical Doctor Association, and Academician Chen Xiangmei, Chairman of Nephrology Committee of China Society of Integrated Traditional Chinese and Western Medicine, gathered in national hotel, Beijing, and read out the "world kidney day Proposal in 2019" and started academic exchanges around this year’s theme.

　　"Everyone enjoys kidney health" aims to further raise people’s attention to the high burden and important harm of kidney diseases around the world, improve the prevention and management strategy of kidney diseases, and call for comprehensive health coverage, prevention and early treatment of kidney diseases. Encourage people to adopt a healthy lifestyle, screen high-risk groups, ensure that patients with kidney disease get the basic health services they need, such as basic physical examination, laboratory tests, and essential drugs, delay the progress of the disease as much as possible, and strengthen advanced health care capabilities to ensure the health of the whole people’s kidneys.

　　However, as one of Chinese’s favorite "tonic" organs, does the public really know about kidneys? Therefore, persistent popularization of popular science is the most important work for medical staff during their stay in world kidney day, which has been done by Beijing nephrologists for 14 years. Every year, through a large number of new media publicity, free clinics, doctor-patient friendship, knowledge lectures and other forms, medical common sense and knowledge of CKD prevention and treatment are popularized to the public, so that many Beijing citizens have obtained correct knowledge of kidney disease. On March 14th this year, on the same day in world kidney day, kidney disease experts from 16 hospitals in Beijing, including xuanwu hospital of Capital Medical University, Fourth Medical Center of the People’s Liberation Army and People’s Hospital of Peking University, walked into Luhe Hospital of Tongzhou affiliated to Capital Medical University and held free clinic and popular science publicity activities. The scene was very warm. "We issued a call to the whole country, and the kidney health of the people in the city and the kidney health of the people all over the country started from this! This is what Beijing experts should do, and it is also what Beijing experts have done well and have always insisted on doing. " Academician Chen Xiangmei affirmed the popular science work of kidney disease in Beijing in the past 14 years.

　　Is your kidney healthy?

　　Academician Chen Xiangmei said in his speech at this conference that this year’s government work report clearly puts chronic diseases at the national prevention and treatment level, and our theme this year, "Kidney health for all", is to extend from disease to the concept of great health, which is very macroscopic and in line with the pulse of the times, in line with the pulse of deepening reform of medical and health undertakings, and what we should do when we enter a new era.

　　At present, compared with cardiovascular disease and diabetes, the popularization of chronic kidney disease in China is not extensive enough, and the medical literacy of the general public needs to be improved. They lack the awareness of actively understanding medical common sense and fail to fully understand the knowledge of preventing kidney disease in time. Moreover, the problem of "expensive and difficult to see a doctor" still exists, which makes some patients fail to see a doctor in time or have regular physical examination. These are important reasons why chronic kidney disease is not easy to be found early.

　　If chronic kidney disease is not prevented early, the condition will gradually progress until uremia develops; It not only damages the health and labor ability of patients, but also brings great pain to patients and even endangers their lives; At the same time, it will also greatly increase the economic burden of patients’ families and society. In fact, the low rate of early prevention and control has brought serious consequences. About 20%-30% patients with kidney disease often find that the renal function damage has developed to an irreversible level when they first visit the hospital.

　　But how can the public judge whether their kidneys are healthy?

　　In fact, it’s very simple, just a simple physical examination. Urine protein and red blood cells in urine routine can basically provide clear signals related to kidney disease.

　　"The key to early interventional therapy is to insist on regular screening every year. Even if there are no symptoms, it is generally necessary to screen urine routine and renal function once a year. If you have hypertension, diabetes, etc., you should check it every six months as appropriate; If you already have certain symptoms, you should go to the hospital for a comprehensive physical examination as soon as possible. " This year’s brochure of world kidney day clearly points out the ways and means.

　　Prevention and treatment of kidney disease starts with healthy living.

　　In recent 30 years, with the improvement of living standards and working conditions of Chinese people, some changes have taken place in people’s traditional lifestyle, such as excessive intake of certain nutrients (carbohydrates, fat, salt, etc.) and reduced physical activity; At the same time, work stress, mental stress, lack of sleep, smoking, alcoholism, environmental pollution and other factors have increased the incidence of metabolic diseases such as hypertension, diabetes, hyperlipidemia, hyperuricemia and obesity, resulting in an increasing prevalence of chronic kidney disease. In addition, drug-induced renal damage caused by drug abuse or irregular use of drugs also showed a significant increase trend.

　　In the academic exchanges at the conference, Professor Li Yuehong’s "What kind of harm does beauty and hairdressing do to the kidney", Professor Tu Xiaowen’s "Smoking and drinking do harm to the kidney", Professor Li Zhongxin’s "The four high protections are not in place, and the kidney is not small", Professor Xiao Yuefei’s "I don’t care if I have a cold and fever, but my kidney is hurt by improper medication" and Professor Zhou Yilun’s "What should I do to protect my kidney" are all easy to understand from the perspective of daily life.

　　At present, the incidence of kidney disease in China is as high as 10.8%, and there are about 130 million CKD patients in China. Looking around the world, there are about 850 million people suffering from kidney disease in the world for various reasons. CKD causes at least 2.4 million deaths every year, and it is currently the sixth fastest growing cause of death.

　　Therefore, Academician Chen Xiangmei suggested that "the participation of the whole people should make people fully realize that CKD is a preventable and treatable disease, understand the characteristics of common diseases, be familiar with the basic knowledge of self-management of diseases, master the skills of healthy lifestyle, and gradually enhance the awareness of disease prevention. It is necessary to change unhealthy lifestyles such as overeating, smoking, excessive drinking and lack of exercise, and prevent and control obesity, hyperlipidemia, hypertension, hyperglycemia, hyperuricemia and abuse.

　　At the same time, experts attending the meeting also called on the whole society to pay more attention and help to CKD patients in spirit, psychology, work, family, economy and life, and strive to gradually realize the beautiful vision that everyone can master medical common sense and enjoy healthy kidneys.

　　Taurus leaves the year with cold wind, and Jade Tiger welcomes the spring with joy. In the Spring Festival of the Year of the Tiger, CCTV-9 has prepared a rich holiday meal for you, which is carefully arranged and presented, and a large film will accompany you for the New Year!

　　Record to accompany you to watch the Winter Olympics and go to the ice and snow appointment!

　　On the evening of February 4th, Diniger, a cross-country skier of China sports delegation, and Zhao Jiawen, an athlete from nordic combined, jointly lit the main torch of the Beijing Winter Olympics. These two contestants representing China are both after 00, full of youth and unlimited potential.

　　Among them, Zhao Jiawen is the first athlete in the history of China to qualify for the nordic combined Olympic Games. Nordic combined is considered as one of the most difficult snow events. In order to get a ticket to nordic combined in the Beijing Winter Olympics, he pushed himself to the wall and practiced hard, hard and hard again. The exclusive behind-the-scenes about his preparations for the Winter Olympics is in the documentary "Flying over the Ice and Snow Line" which was hit by CCTV-9!

　　The documentary "Flying Over the Ice and Snow Line" was jointly produced by the Film and Television Documentary Center of the General Station and Insight TV of the Netherlands. Ice and snow athletes (teams) from different countries in the world were selected to track and film their struggles in preparing for the 2022 Beijing Winter Olympics, tell their moving stories in their sports careers and real life, and carry forward the sportsmanship of climbing the peak and the lofty feelings of winning glory for their country.

　　Gu Ailing, a talented girl of freestyle skiing in China, Kay Wilby, a famous short track speed skater in the Netherlands, Alice meriwether, an alpine skier in the United States, Donovan Carrillo, a figure skater in Mexico, Katie Ormerod, the Duchess of Artificial Ski Slope in Britain, and Zhao Jiawen, an athlete in nordic combined, China, as the protagonists in the film will bring their wonderful life stories to the audience. The film triggered a warm response after the premiere of CCTV-9, and returned domineering during the Spring Festival, once again shining on the screen.

　　The documentary series "Great Winter" takes the long history of development, sports principles and scientific highlights of the Winter Olympics as the core, and combines the scientific and technological knowledge of the Beijing Winter Olympics venues, scientific training AIDS, etc., with a large number of animation expressions and interesting ways of popular science experts to vividly explain, showing the uniqueness of the Winter Olympics sports from multiple angles and in depth.

　　The micro-documentary "Below Zero" revolves around the 15 events of the Beijing Winter Olympics &mdash; &mdash; Alpine skiing, biathlon, snowmobile, cross-country skiing, curling, figure skating, freestyle skiing, ice hockey, sleigh, nordic combined, short track speed skating, steel snowmobile, platform skiing, snowboarding, speed skating, etc., with the length of 5 minutes per episode, introduce the most extreme characteristics of a Winter Olympics event and popularize the knowledge of ice and snow sports.

　　Records accompany you to see the mountains and rivers and meet the ultimate China!

　　During the Spring Festival of the Year of the Tiger, two nature documentaries, Meeting the Extreme China and Chasing Fish in the Sea, will show you the ecological beauty and human brilliance in extreme environment from a multi-dimensional perspective.

Stills of "Meeting the Extreme China"

　　"Meeting the Extreme China" is a documentary about China’s most magical natural home, covering seven extreme landscapes of China: from the largest continental glacier in the world &mdash; &mdash; Puruogangri ice sheet, to the world’s largest mobile desert &mdash; &mdash; Taklimakan desert; From the extreme cold in the northernmost part of China &mdash; &mdash; Genhe and Mohe, to the largest and deepest canyon in the world &mdash; &mdash; Yarlung Zangbo Grand Canyon; From the largest and richest karst landform area in the world &mdash; &mdash; Karst in southern China, a wonder of the world where rivers flow side by side &mdash; &mdash; "Three Parallel Rivers" area, and then to the northernmost river confluence sea in China &mdash; &mdash; Yellow sea and Bohai sea

　　In the most typical season and the most critical moment, the film crew of Meet the Extreme China went deep into these unique extreme places and led the audience to feel the natural power and the miracle of life.

　　The documentary "Chasing Fish in the Sea" fully shows the process of China’s fleet’s offshore fishing, so that the audience can form an overall understanding of the development and progress of offshore fishing in China and feel the professionalism and survival wisdom of "deep-sea hunters". Focusing on offshore fishermen, the film depicts a group of optimistic, fearless, generous and simple "pure men" at sea while presenting their fantastic and arduous journey, which is unforgettable.

　　Record the delicious food with you and start the taste journey!

　　From Baishan Blackwater to the southwest border, from the land of abundance to Guanzhong Plain, the film crew of "The Journey of Pepper" went deep into the frontiers, coasts, plateaus, jungles and cities, and explored the deep-seated reasons why peppers changed the style of Chinese’s food culture while showing regional delicacies related to peppers.

　　How do Jinuo villagers in Xishuangbanna make festive delicious "chopped raw" with peppers? How delicious is the spicy braised duck palm produced in Longyou, Zhejiang Province, which is rich in white pepper? Quanzhou, the starting point of the Maritime Silk Road, has changed from a place that never likes spicy food to a "spicy addiction" resort where Southeast Asian snacks gather. What kind of process has it gone through? I believe you will know after watching this six-episode documentary!

　　"Taste of Macao" is a 4K documentary jointly produced by the Central Radio and Television General Station and the Macao New Port District Federation of Industry and Commerce, with a total of four episodes. After being broadcast on CCTV-1, CCTV-9 and CCTV video at the end of last year, it was well received by the audience and was praised as the "mini-encyclopedia" of Macao food circle. Professor Zhang Tongdao, director of the Documentary Research Center of Beijing Normal University, Ceng Dian praised the film: "The cultural collision carried by food is beautiful and warm, and Taste of Macau is not only a mouth-watering feast, but also a thought-provoking journey."

　　The new film "Taste Expensive and Spicy" and "Four Seasons Flowing New Year’s Eve" was released in the Spring Festival, offering the audience a unique and affectionate New Year’s Eve dinner and expressing Chinese’s deep feelings for the New Year, hometown and home.

　　Chinese New Year is coming, whether you are in a foreign land or returning to your hometown, please come to CCTV-9. Wash the dust in the documentary world, travel across all corners of the country, taste the delicious food on earth, and meet the ultimate China!

　　Xinhua News Agency, Beijing, February 21st(International observation) The annual report on trade with China is greatly popular. There is no market for "decoupling theory"

　　Xinhua news agency reporter

　　Recently, many major economies in the world published the annual trade reports with China in 2022, and a number of bilateral trade data with China reached record highs, with frequent highlights of economic and trade cooperation, showing that economic and trade ties with China are getting closer and cooperation with China’s supply chain is more resilient.

　　International observers believe that the red-hot annual trade reports of major economies with China have greatly boosted the confidence of countries in China’s economy and win-win economic and trade cooperation with China, and also clearly showed that the "decoupling theory" advocated and manipulated by American politicians with China is not accepted by the market.

　　Closer ties: the trade volume with China has reached record highs.

　　Looking at the trade data of major countries and regions with China in 2022, many countries and regions have stronger trade performance with China than with other major trading partners, which not only maintains the growth trend, but also exceeds their overall foreign trade growth rate.

　　According to data released by the US Department of Commerce on the 7th, according to US statistics, the total trade volume of goods between the United States and China in 2022 reached US$ 690.6 billion, a record high. The American media believe that it is "surprising" that the US-China trade data reached a new high in 2022, considering that the United States has imposed tariffs on China’s goods exported to the United States for many years and that the US government has blocked the exchanges between China and the United States on the grounds of "national security", which fully proves that bilateral economic and trade relations are still close.

　　According to data released by Eurostat on the 15th, the total trade volume of goods between Europe and China reached 856.3 billion euros in 2022, an increase of about 23% compared with 2021, which also reached a new high.

　　According to the latest data from the German Federal Statistical Office, the total trade volume between Germany and China rose to a record level of 297.9 billion euros in 2022, an increase of about 21% compared with 2021, which was higher than the overall growth rate of German foreign trade in the same period. China has become the most important German trading partner for the seventh consecutive year.

　　Juergen Martes, an expert at the German Economic Research Institute, said that China’s economy is huge, and the economic and trade ties between Germany and China are closer. No one wants to and cannot "decouple" from China.

　　According to the data released by the General Administration of Customs of China, in 2022, the bilateral trade volume between China and Africa, ASEAN and Latin America reached US$ 282 billion, US$ 975.3 billion and US$ 485.8 billion respectively, increasing by 11.1%, 11.2% and 7.7% respectively compared with 2021, all of which were record highs.

　　Former Croatian Minister of Economy Ljubo Jurcic told Xinhua News Agency that although the COVID-19 epidemic has brought some impact, China’s economy has maintained a relatively high growth rate for many years, which is the "locomotive" for stimulating world economic growth. Politicians and media in a few western countries concocted the decoupling theory with China because they ignored or didn’t want to see the fact that the world was closely linked with China.

　　More dividends: complementary advantages to achieve a win-win situation

　　Under the market law of complementary advantages and mutual benefit and win-win, the economic and trade cooperation between countries with China is full of vitality.

　　In view of the new trend of German-Chinese trade in 2022, the German Economic Research Institute reported that the increase in international energy and raw material prices aggravated inflationary pressure, and affordable goods produced in China were more favored by the German market. In addition, German enterprises have gradually increased their investment in China and localized production, which is also reflected in the trade data.

　　In the past year, automobiles were the main highlight of bilateral trade between Mexico and China. According to the data of National Geographic Statistics Bureau of Mexico, in 2022, China cars accounted for nearly a quarter of the imported cars in Mexico. China has surpassed the United States, Japan and other countries to become the main source country of Mexican imported cars.

　　According to the latest data from the National Statistics and Census Institute of Argentina, China will be Argentina’s second largest export destination and largest import source in 2022. Compared with 2021, Argentina’s import and export of goods to China in 2022 increased by 29.4% and 27.4% respectively.

　　Pablo Levinton, a professor of economics at Ranus National University in Argentina, believes that the economies of Argentina and China are highly complementary. Argentina’s high-quality beef, red wine and other products are welcomed by the China market, and Argentina’s lithium, copper and other mineral resources are also needed by China’s new energy industries.

　　The North Africa Post commented that Africa-China trade reached a new high. Africa has expanded its exports to China with the advantages of natural resources such as crude oil, copper, cobalt and iron ore, while China’s products such as machinery, electronics and textiles meet the demand of the African market.

　　Bambang Suryono, Chairman of the Asian Innovation Research Center, an Indonesian think tank, said that the bilateral trade volume between Indonesia and China increased by nearly 20% in 2022 compared with the previous year, and China continued to be Indonesia’s largest trading partner, demonstrating the high correlation and complementarity between the two economies. China is Indonesia’s largest export market, and its rapid economic growth will greatly promote Indonesia’s economic and social development.

　　More Confidence: Looking forward to the "East Wind" in China Market

　　Looking forward to the new year, many institutions and analysts are optimistic about the prospects of China-foreign trade and economic cooperation, and believe that China’s economy will make generate more dynamic and bring more market opportunities and development dividends to the world.

　　According to Chilean customs statistics, Chile’s exports to China in 2022 were US$ 38.106 billion, accounting for 38.9% of the country’s total exports. China has been Chile’s largest trading partner since 2009. Nearly 90% of Chile’s cherry exports are sold to China market.

　　"The China market is too important for us!" Ivan Marambio, president of the Chilean Fruit Exporters Association, said. After China implemented the temporary measures for personnel exchanges between China and foreign countries in early January, he led a delegation to visit several cities in China to negotiate with business partners. "We are optimistic about China’s market resilience and consumption vitality, and hope to achieve greater development through the China market".

　　In 2022, China became Brazil’s largest trading partner for the 14th consecutive year. According to official Brazilian data, Brazil’s exports to China reached US$ 89.428 billion last year, accounting for 26.8% of the country’s total exports.

　　Jose Ricardo Luce Jr., CEO of Brazilian business leaders’ organization in China, said that the deepening economic and trade partnership between Brazil and China has had a positive impact on the development of Brazil’s agriculture, infrastructure, science and technology and e-commerce. Bilateral trade between Pakistan and China has continuously hit new highs, which has contributed greatly to Brazil’s economic growth and will further promote exchanges between the two sides in various fields.

　　The African Development Bank released a report in January, raising the economic growth forecast of Africa to 4% in 2023. According to the report, after China optimizes and adjusts its epidemic prevention policy, Asia, as an important export market of Africa, will achieve steady growth, thus expanding the development space of Africa.

　　Ralph Klein, general manager of German Haoting Electronics Company, said that China has great market potential, and China’s economy has a great influence on the development of German enterprises in China, expecting China’s economy to achieve more positive development and faster growth.

　　According to the data released by the National Bureau of Statistics on February 17th, in 2022, China was the second largest trading partner of Britain in terms of goods import and the fifth largest trading partner in terms of goods export. Zhang Zhikai, a scholar at Durham University in the UK, believes that British exports to China have increased, driven by diversified trade demand. British business circles are actively promoting economic and trade exchanges between Britain and China, and bilateral trade is expected to grow further this year.