Recently, MediaTek unveiled its new generation flagship 5G generative AI mobile chip Tianji 9300. The innovative all-core architecture design combined with the new generation AI processor APU and MediaTek’s unique cutting-edge technology, its powerful performance provided support for generative AI applications and created a vivid and substantial generative AI experience. At the same time, MediaTek shared resources with many AI companies in the industry, and jointly created an adequate AI ecosystem on the mobile side.

The brand-new seventh-generation AI processor APU 790 is born for generative AI.　　　　　

With the increasing demand of users for generative AI applications, the advantages of end-side generative AI such as convenience and security are highlighted. Of course, deploying the end-side AI language model requires strong AI computing power support.

Tianji 9300 is equipped with MediaTek’s seventh generation AI processor APU 790, which is designed for generative AI. It has a hardware-level generative AI engine, which can realize higher-speed and safer edge AI calculation, and deeply adapt to Transformer model for operator acceleration, with a speed eight times higher than that of the previous generation.

At the same time, the performance and energy efficiency of APU 790 have been significantly improved, and the integer operation and floating-point operation capabilities have been improved to twice that of the previous generation. Zurich ETHZv5.1 AI-Benchmark Mobile Soc scored 2109 points, and the AI performance successfully dominated the list, and the power consumption was reduced by 45%. With the support of powerful AI performance, images can be generated within 1 second. Tianji 9300′ s powerful AI computing power, innovative all-core CPU architecture and Immortalis-G720 GPU all lay a solid performance foundation for end-to-end running of generative AI.

At the same time, based on the characteristics of the large language model with hundreds of millions of parameters, MediaTek has developed the mixed-precision INT4 quantization technology, which, combined with the memory hardware compression technology of MediaTek, can make more efficient use of memory bandwidth, greatly reduce the terminal memory occupied by the large AI model, break through the memory limit of mobile phones for running the large AI language model end-to-end, and help the larger parameter model land on the end-side.

Based on the above, Tianqi 9300 landed a 7 billion-parameter AI language model on the side of vivo flagship mobile phone for the first time, with a processing speed of 20 Tokens per second. Not only that, MediaTek has broken through the industry limit, and has successfully run a large language model with 13 billion parameters on the end side with vivo. Even, Tianji 9300 has taken the lead in successfully running the AI language model with 33 billion parameters on mobile chips, leading the industry.

Tianji 9300 also supports multi-modal generative AI model, creating rich and interesting end-to-end experiences such as "Wen Sheng Poetry", "Wen Sheng Picture" and "Wen Sheng Interesting Picture".

It can be seen that Tianqi 9300′ s AI computing power and end-to-end generative AI capability are ahead of the industry, which is enough for users to be full of AI creativity anytime and anywhere.

The end-side skill expansion of generative AI model brings comprehensive and rich end-side generative AI experience.

Different from the cloud-side generative AI solution, due to the difference of hardware environment, the deployment of end-side generative AI also needs to consider factors such as mobile phone memory, storage capacity, and upper load limit. Therefore, MediaTek took the lead in proposing advanced solutions.

APU 790 supports NeuroPilot Fusion, an end-side skill expansion technology of generative AI model. It can continuously carry out LoRA (Low-Rank Adaptation) fusion on the end-side based on the basic big model. With the empowerment of hybrid AI, it can complete the fusion of n functions on the end-side based on one basic big model through cloud training, giving the basic big model more comprehensive and richer generative AI application capabilities.

For example, based on the "drawing GIF animation" function of the AI model end-side skill expansion technology, users can change different styles or even expressions according to a photo, and play an expression pack with a personal style, and the second expression pack is small.

NeuroPilot, an AI development platform, accelerates the end-side generative AI ecological layout.

Based on powerful AI computing power, advanced memory hardware compression technology and AI model end-side skill expansion technology, the APU 790 of Tianji 9300 has raised the speed and breadth of end-side generative AI to a new level. At the same time, in order to accelerate the deployment and popularization of generative AI in the end-side, MediaTek has also built a rich AI ecosystem with its AI development platform NeuroPilot, from the underlying hardware to the tool chain, model center and development ecosystem, helping the ecosystem to deploy end-side generative AI applications quickly and efficiently.

NeuroPilot, the AI development platform, supports leading-edge mainstream AI models such as Android, Meta LIama 2, Baidu ERNIE Bot Model and Hundred Rivers Intelligent Hundred Rivers Model.

More importantly, NeuroPilot has a complete and advanced tool chain, including low-rank adaptive fusion of NeuroPilot Compression, Speculative Decoding acceleration and model optimization and transformation technology.

MediaTek Tianji Developer Center can also provide one-stop developer resources for end-side generative AI landing, and share end-side model deployment cases to improve development efficiency. At present, more than 20 generative AI partners have joined the ecological co-construction.

MediaTek also works with industry contract partners to create a wonderful generative AI application experience. ArcSoft’s generative AI super-resolution technology is based on the edge computing power of Tianji 9300 APU, and its performance can be improved by 30% compared with the previous generation. When shooting at a magnification of 25 times, using the generative AI super-resolution technology, you can shoot more realistic image effects.

The generative AI semantic search technology of Extreme Sense Technology is also based on the edge computing ability of Tianji 9300 APU. Compared with the previous generation, the performance can be improved by 260%. For example, searching for photos in the photo album of a mobile phone and describing the content of the photos can accurately find the corresponding photos in milliseconds. Moreover, it can also be searched when the network is disconnected, and privacy will not be revealed.

Morpho’s video call real-time digital avatar generation technology is also based on the edge computing ability of Tianji 9300 APU, and its performance is improved by 26% compared with the previous generation. The general virtual portrait generator needs to manually select the appearance style, which takes time. However, based on the video call real-time digital avatar generation technology, the user can operate easily, and the digital avatar can be generated instantly only by opening a single frame of the camera.

Based on the edge computing ability of Tianji 9300 APU, the performance of Hui carp’s generative AI anti-glare technology can be improved by 60%. With the help of this technology, whether outdoors or indoors, if there is glare when shooting, you can eliminate glare interference as long as you relax and darken it.

It can be seen that under the trend of AI-side cloud convergence, Tianqi 9300 has shown comprehensive advantages in AI computing power, generative AI user experience and ecology, setting a new benchmark for a new generation of flagship end-to-end generative AI experience, and powerful generative AI will use Tianqi.

In addition, MediaTek and other pioneers of generative AI are constantly carrying out technological innovation and ecological layout, vigorously promoting hybrid AI computing, providing a unique and efficient solution for end-to-end generative AI deployment, and devoting themselves to promoting the widespread application of generative AI at the end-side, so that more users can experience personalized end-to-end AI applications and build a new panoramic intelligent experience, thus enabling technology to better serve the public.

　

Dancing, reading, fitness … Here, everyone can always find their own interesting activities, and walk into the "Neighborhood Home" activity center for the elderly at No.1 Yintian Changxing Lake, Changxing Community, Guankou Street, Liuyang City. It is a "base" for residents’ activities and a "conference hall" for residents to make suggestions and suggestions.

On April 26th, the "Good Neighborhood House" was officially unveiled with the cheers of everyone. Combined with local conditions, the street adheres to the way of party building leading, government leading and social participation, and builds the "Neighbourhood House" of Yintian Changxing Lake No.1, which realizes the construction of leisure activities venues integrating table tennis room, chess room, reading room and conference hall, and also provides services such as rest, drinking water and emergency charging to meet the diversified service needs of residents. At the same time, we will set up functional areas such as "Hello Neighbor Neighborhood Council" and Neighborhood Pioneer Post, extend the service "tentacles" of the Party organization from the general branch of the community to the districts and communities, and build red positions around the residents to realize community governance and residents’ service at the same frequency.

At the beginning of the construction, the general party branch of the community took the lead, with the participation of the community party branch, the industry committee, the property company, the members of the volunteer service team and the neighbors. Relying on the red platform of the community, the opinions of the masses were fully collected, and the residents’ representatives were mobilized to hold a good-neighborly meeting. After many discussions, it was finally unanimously decided that the community party branch would take the lead, the industry committee would raise funds, and the elderly association would assist in the management, so as to build a "good-neighborly house" of about 400 square meters on the eight overhead floors of the community. Really make "small things about people’s livelihood" a major event of "benefiting the people and benefiting the people".

At the opening ceremony of the Good Neighborhood House, the neighbors got together, singing and dancing. Accompanied by cheerful music, the performance kicked off in the opening dance of "Gathering Together". The dance "I Love Beautiful China" and other programs fully demonstrated the vitality and spiritual outlook of residents, and condensed and conveyed the positive energy among neighbors.

"Now, we have our own activity center. I dance when the weather is fine, and play chess and ball games when it rains. It’s really good …" Liu Yi, 58, said happily, waving a ping-pong bat, "Neighborhood House" has built a communication platform for residents, which has brought neighborhood relations closer, enhanced neighborhood feelings and further enhanced the sense of belonging and happiness of community residents.

Complete convenience service facilities, comfortable chairs and sofas, neatly arranged books … This warm and diverse neighborhood space closely revolves around the working idea of "co-construction, co-governance and sharing", and strives to extend services to people’s doorsteps and send warmth to people’s hearts.

In recent years, Guankou Street has actively built a "good neighbor’s house" activity position, and carried out neighborhood cultural activities in a normal way, so that "strangers" become "friends" and "friends" become "relatives". In the next step, Guankou Street will be guided by residents’ needs and rely on the "Good Neighborhood House" to carry out a variety of neighborhood activities to create a "happy life circle" with more family flavor and human touch. (Li Chunlan, Zhang Huizhi)

　　As the saying goes, "a thousand dollars can’t buy old people to lose weight." Nowadays, many old people have joined the army to lose weight, and it seems that they will be healthy if they lose weight. Recently, a study published in the American Obesity magazine shows that the elderly’s deliberate weight loss may affect their bone health.

　　Body mass index BMI= the square of weight/height, which is an accepted standard to measure obesity. In this study, 77 students with an average BMI of 33.6 (usually 18.5≤ BMI index ≤ 23.9 old people with normal weight, more than 29.9 are severely obese) were given weight-loss intervention for 18 months, and the overall weight of the old people and the bone mineral density of the areas (total hip, femoral neck, lumbar vertebrae and trabecular bone) were monitored and scored at 18 months and 30 months. The results show that the decline of hip bone mineral density will last for one year after weight-loss intervention for elderly obese patients, whether they rebound or not. The study also found that fat loss and weight loss reduced the bone mineral density of hip and increased the risk of osteoporosis.

　　Gou Bo, a professor in the Department of Health Sciences of Xi ‘an Institute of Physical Education, said that if the elderly lose weight improperly, such as excessive diet control, resulting in insufficient nutrition intake, or lose weight too much and too fast, resulting in significant weight loss, it will lead to a decline in bone density. Older people do not have to lose weight if they are only slightly obese and have no obvious cardiovascular disease. If there are some contraindications to exercise, and it is not suitable for exercise to lose weight, you can seek nutrition, medical care and other methods to control your weight under the guidance of a doctor. If obesity is accompanied by other chronic diseases, lose some weight appropriately. In principle, adopt safe and effective methods to achieve the goal at a slower speed such as diet control and exercise.

　　Many old people find that even if they eat and exercise as much as when they were young, it is easy to "gain weight". The reason is that the basal metabolic rate and muscle mass of adults decrease year by year with age. Therefore, even if the elderly eat less, their digestion and absorption ability are poor, and the balance of energy in and out is still "less in and out", in which case it will be "fat".

　　Gou Bo emphasized that obesity will directly affect heart function and vascular health, and it is easy to suffer from various cardiovascular and cerebrovascular diseases. The ideal situation is to "gain muscle and lose fat" on the premise of ensuring basic nutrition.

　　Old people can’t take extreme measures to lose weight, let alone go on a diet like young people. We can start with the moderation and choice of dinner, eat some coarse grains instead of staple food, eat food with high protein content for breakfast, and control the staple food at about 2 Liang at noon. It is not recommended to choose diet pills or surgery to lose weight.

　　In sports, it is suggested that aerobic exercise should be combined with strength training, and it is best to take some soothing forms, such as Tai Ji Chuan, yoga, walking, etc. As long as you can persist every day and achieve a certain amount of exercise, you can lose weight completely.

　　Interviewed expert: Professor Gou Bo, Department of Health Sciences, Xi ‘an Institute of Physical Education

According to CCTV news, the reporter learned from the press conference on the prevention and control of COVID-19 epidemic in Baise City, Guangxi Province held in Debao County on the afternoon of the 14th that some people found that they had never been to medium and high-risk areas, but the health code turned into a yellow code or a red code. If this happens, it can be transcoded in the following ways:

First, through the abnormal feedback function of Guangxi Health Code-Scan Code Anti-epidemic applet, we can make independent complaints about personal health code abnormality, upload screenshots of travel cards, screenshots of nucleic acid detection reports, health commitment letters and other supporting materials, and the administrators of counties, townships or towns, streets and districts will complete the processing within 24 hours after receiving the information reminder of the health code abnormality feedback processing list within their jurisdiction.

The second is to report to the unit, the property of the residential area and the local community and village by telephone. By the county or township, street zoning administrator to meet the conditions of restoring the green code personnel transcoding.

Third, other situations can be consulted and reflected through the 12345 hotline.

Editor Zhao Xi

At one o’clock this morning, the annual "Spring Festival Evening" in the science and technology circle-Apple Autumn New Product Launch Conference was held in Apple Park Park. The good news is that this time Apple launched three new iPhone：iPhone XS, iPhone XS Max and iPhone XR. The bad news is that the prices are not "close to the people", especially the largest iPhone Xs Max, with a maximum price of 12,799 yuan. Earlier, some netizens laughed and said, "If you can’t afford it, you will stay up late to watch the live broadcast. Local tyrants will wake up and buy it directly!" This article will take those friends who are neither local tyrants nor watching the live broadcast to relive the dry goods of the conference.

Focus!

1. Apple released three new iPhones, the model of which is iPhone XS/XS Max/XR, and an Apple Watch Series 4； that supports ECG function;

2, the strongest mobile phone chip in history, three new iPhone products all adopt Apple’s latest bionic chip A12；;

3. The China version of iPhone XS Max and iPhone XR have added support for dual card dual standby, which is the first time in the history of Apple mobile phones;

4, the price hit a new high, the highest price of iPhone XS Max licensed is 12,799 yuan.

5, Apple Watch Series 4 is equipped with a new S4 chip, which supports ECG ECG function.

It is worth mentioning that after three new iphones were put on the shelves of Apple official website, last year’s iPhone was officially discontinued in Apple official website. However, the previous flagship models-iPhone 8 and iPhone7-are still available for sale. The official explanation given by Apple is that users can buy iPhones through authorized dealer channels. Although the price of iPhone has been reduced by nearly 2,000 yuan, it is still higher than that of iPhoneXR just released. Presumably, people who plan to buy iPhone may be more willing to save a few hundred yuan to buy a new iPhone equipped with Apple A12 processor.

Now, let’s see what else.futuristic techBirth ▼

Double card and double standby, underwater bubble for 30 minutes without pressure.

After 10 years, the iPhone finally supports dual cards! IPhone XS Max supports dual card dual standby.

Apple made a dual-card version specially for China. IPhone XS Max can insert two cards directly, using the design of inserting cards on the front and back of a single card slot similar to OPPO Find X. (Dual telecom cards are not supported)

In addition, waterproof has reached the level of IP68, which means that the mobile phone can be placed under water for up to 30 minutes. If you accidentally drop it in the swimming pool, it doesn’t matter. Pick it up, blow it again, and it will be fine when it is dry.

"The first 7 nm A12 bionic biochip in the industry"

All three new iPhone products use Apple’s latest bionic chip A12.

Last year, the operation of A11 bionic chip could reach 60 million operations per second, so in A12 bionic chip, the operation data per second reached 5 trillion.

This power is mainly reflected in the following points:

The first is display performance.For example, portrait mode, portrait lighting effect, animated expressions, AR experience, Siri shortcuts, etc. all have great demand for neural network engines.

Followed by the AI camera.IPhone XS and iPhone XS Max have wide-angle and telephoto rear cameras, both of which are 12-megapixel sensors. A12 chip can automatically perform exposure or white balance, and can also reduce dryness.

In the portrait mode of the camera, the depth of field function is also added, so that users can automatically isolate the subject and blur the background, and the effect is very good.

Apple Watch Series 4

Apple also launched the Apple Watch Series 4 smart watch today, which is the first major design transformation of Apple Watch in more than three years-the most intuitive improvement is a larger display with radians and almost no borders at the edges.　

The dial can display more information (BBC).

The biggest highlight is its health functions, including:Measure heartbeat and abnormal prompt、Fall detectionandSOS emergency contactandElectrocardiogram generating function . Users can also put their fingers on it at any time to see the real-time ECG and heart rate, and the whole process takes only 30 seconds.　

Version and price

There are two versions of Apple Watch Series 4, the separate GPS version starts at 3199 yuan, and the GPS+cellular network version starts at 3999 yuan.

Sale time

Ordering began on September 14th, and it will be released on September 21st.

The fruit powder cried and Huawei smiled …

As soon as the price of the new iPhone was announced, fruit powder said "can’t afford it".

However, there is another episode: at about 3 o’clock, Yu Chengdong, senior vice president of Huawei Technologies Co., Ltd., wrote in his personal Weibo:Steady, I’ll see you in London on October 16th!Subsequently, Huawei PK Apple’s brand spoof map appeared on the Internet.

It seems that after reading the conference, Huawei is very confident. As for the people who eat melons, it is still the price issue that is more spit.

Do you want to buy the new iPhone? Have you paid off last year’s installment?

Source: Qilu Net Comprehensive People’s Network, WeChat public number: ZEALER, Popular Science China, 21st century business herald, Sina Weibo.

Professor Yang Xichuan, Original Professor of Xichuan Xiaoliang Dermatology

| Editing/Typesetting: Fanny Editor: kiki&Jeing Audit: Li Yun

Fact is stranger than fiction. There are thousands of diseases in the world, which are particularly strange and rare?

Today, Xiao Liang, a boy♂ who is keen on studying the mysteries of the body, will take you close to science and learn about four bizarre and rare human diseases that may be unknown to 90% people (strange knowledge has increased again).

Please note that there is continuous high energy ahead, and timid students should be careful ~

NO.1 Shuren disease: hands and feet are covered with "branches and roots"

I’m sure you’ve all heard about vegetative state, but have you ever heard of Shuren? What do you think of first? The cute Groot in Marvel Comics’s movies?

(Source: dribbble/Hancooock)

The tree people in the movie can love each other, but in real life, the "tree people" have to suffer from "tree people’s disease".

Shuren’s disease, medically known as "epidermodysplasia verrucosa", is a rare hereditary skin disease caused by human papillomavirus (HPV) infection, which may be related to gene mutation. It usually begins between the ages of 4 and 8, and most often begins before the age of 20.

People with Shuren’s disease usually grow many sarcomas, maculae and papules that look like branches and roots on their hands and feet, which not only affect the appearance, but also make it inconvenient for daily life, and also turn into skin cancer with high winds.

(Indonesian man suffering from Shuren disease)

Unfortunately, there is no unified and effective solution to this disease at present. Some studies think that retinoids can improve it to some extent. In addition, patients should avoid excessive sun exposure, and if they are prone to cancer, they should be operated immediately or removed by other methods.

NO.2 Premature senility: 7-year-old age and 70-year-old appearance

Anti-aging is the pursuit of many people. Who doesn’t want to be younger and more energetic every year? However, in this world, some people actually get old and even die early at a young age because of a rare genetic disease-premature senility.

Art comes from life. It is said that the film "The Curious Case of Benjamin Button" (also known as "Rejuvenation") may be inspired by premature senility, but the time sequence is reversed. The hero of the film looks like an old man of 70 or 80 at birth. As time goes by, the people around him are getting older, but he is rejuvenating, getting younger and younger, and finally returning to the baby form and dying in the arms of an old lover.

(Source: Movie "The Curious Case of Benjamin Button")

If the protagonist’s life is a bizarre movie, then in reality, patients with premature senility live a life like pressing the acceleration button, aging faster than their peers, feeling the rapid failure of every body organ every day, and dying before they bloom.

There are some heartbreaking facts about premature senility:

● Premature senility in adults: Patients usually develop normally before puberty. At the age of 20-30, they begin to have aging characteristics such as skin wrinkles, muscle atrophy, gray hair and shedding, and the average age of death is 47 years old.

● Premature senility in children: The patient is normal at birth, but after birth, the appearance and body organs will accelerate the aging and decline, and with the increase of age, he will suffer from various diseases such as cardiovascular disease, and the average age of death is only 13 years old.

(patients with premature senility)

NO.3 Vampire: You can only live in darkness.

Legend has it that there are zombies in the East and vampires in the West. Speaking of vampires, you may think of the handsome "ghosts" of noble Leng Yan in film and television dramas. In real life, many people are willing to believe that vampires exist in some corner of the world, but in the medical field, "vampires" really may exist, and they are porphyria patients.

You can slide left and right to view the picture, but it is recommended to slide carefully!

Porphyrin (bD lí n) disease is a rare metabolic disease caused by the lack of enzyme activity in heme biosynthesis pathway, which leads to abnormal increase of porphyrin or its precursor concentration and accumulation in tissues, resulting in cell damage. In 2020, experts in the diagnosis and treatment of porphyria agreed to divide porphyria into the following categories:

(Source: Literature [4])

When the medical profession knew nothing about porphyria hundreds of years ago, patients with porphyria were often considered as legendary vampires, which may be because some symptoms of porphyria are very similar to the image of vampires.

photophobia

People suffering from porphyria will be as afraid to be exposed to the sun as vampires, because they will get sick when they see light, and their skin will have photosensitive reaction, blisters, scars, deformities, etc., and in severe cases, they may be accompanied by the loss of fingers, eyelids, nose and ears.

"bloodthirsty"

Unlike vampires who directly suck people’s necks to drink blood, porphyria patients are "bloodthirsty" by blood transfusion to achieve treatment and relief.

Look different from ordinary people

The high level of porphyrin in red blood cells of patients with porphyria can lead to hemolysis, and severe hemolysis often leads to anemia, so it may cause pallor.

However, people with congenital erythropoietic porphyria will show red or brown color in their teeth, bones and urine due to excessive porphyrin, and they will fluoresce when exposed to ultraviolet rays, which really looks a bit like vampires who have just eaten their children.

NO.4 werewolf syndrome: a real hairy child

Everyone has Mao Mao, but people with werewolf syndrome have a lot of Mao Mao.

However, this werewolf is not a werewolf. The so-called werewolf syndrome actually refers to "congenital systemic hirsutism". The patient’s whole body is covered with thick hair, which is beyond the normal physiological range of the same age, gender and race, and seems to be the image of a werewolf in our impression. In addition to excessive hair, it is usually accompanied by facial deformities.

(Source: Literature [6])

The prevalence rate of werewolf syndrome is extremely low, and it was once considered as an "atavism" phenomenon. However, at present, most studies believe that patients suffer from this disease because of unknown genetic defects.

Patients with the above diseases are often noticed by people in their daily lives because of their abnormal appearance, but who doesn’t want to be healthy and safe in life, and who would like to do so if they could start over.

When you meet them in your life, please be less discriminating and misunderstanding, and more understanding and kindness. I also hope that medical technology will be more developed in the future, so that these special patients can get better treatment and return to ordinary people’s lives.

[References]

[1]Agharbi FZ. Epidermodysplasie verruciforme: à propos d’un cas [Epidermodysplasia verruciformis: about a case]. Pan Afr Med J. 2018 May 29; 30:78. French. doi: 10.11604/pamj.2018.30.78.16058. PMID: 30344862; PMCID: PMC6191268.

Yang Hui, Liu Wan, Chang Jianmin. Verrucous epidermal dysplasia [J]. Journal of Clinical Dermatology, 2015:13-14.

Wang Zehua, Li Hongyu, Qu Jing, Zhang Weiqi, Liu Guanghui. Pathogenesis and intervention methods of human premature senility [J]. Progress in biochemistry and biophysics, 2018,45(09):926-934.

[4] Erythrocyte Disease (Anemia) Group, Hematology Branch, Chinese Medical Association. Expert Consensus on Diagnosis and Treatment of Porphyrin Disease in China (2020) [J]. Chinese Medical Journal, 2020,100 (14): 1051-1056.

[5]Pavone P, Praticò AD, Falsaperla R, Ruggieri M, Zollino M, Corsello G, Neri G. Congenital generalized hypertrichosis: the skin as a clue to complex malformation syndromes. Ital J Pediatr. 2015 Aug 5; 41:55. doi: 10.1186/s13052-015-0161-3. PMID: 26242548; PMCID: PMC4526284.

[6]Sun M, Li N, Dong W, Chen Z, Liu Q, Xu Y, He G, Shi Y, Li X, Hao J, Luo Y, Shang D, Lv D, Ma F, Zhang D, Hua R, Lu C, Wen Y, Cao L, Irvine AD, McLean WH, Dong Q, Wang MR, Yu J, He L, Lo WH, Zhang X. Copy-number mutations on chromosome 17q24.2-q24.3 in congenital generalized hypertrichosis terminalis with or without gingival hyperplasia. Am J Hum Genet. 2009 Jun; 84(6):807-13. doi: 10.1016/j.ajhg.2009.04.018. Epub 2009 May 21. PMID: 19463983; PMCID: PMC2694973.

[disclaimer]

The data in this article was updated on May 14th, 2021.

It was originally written by Professor Yang Xichuan, a dermatologist, aiming at popularizing science for readers.

Popular science content can not replace doctors’ diagnosis and treatment opinions, and is for reference only.

If you have skin problems, please consult a doctor in time.

Some pictures are from the Internet. If there is any infringement, please contact to delete them.

Cover image source: blurrr

Read the original text

　　China Overseas Chinese Network March 1st Issue: From March, these new regulations will affect the lives of overseas Chinese!

　　The season has passed the rain, and Miss Chun’s footsteps are getting closer and closer. Looking around, maybe it’s still "the grass looks close but there is nothing", but I believe that "the branches of red apricots are full of spring" is not far away.

　　A year’s plan starts with spring. Xiaoqiao first wishes everyone a good start, a good step and a full and wonderful 2019.

　　In March, what major events are about to happen? What new rules will affect the lives of overseas Chinese? Xiao Qiao will show you below.

　　March event: the two sessions of the National People’s Congress are about to start.

　　The second session of the 13th National People’s Congress and the second session of the 13th National Committee of the Chinese People’s Political Consultative Conference will be held in Beijing on March 5 and March 3, 2019, respectively.

　　At that time, NPC deputies and CPPCC members from all walks of life will shoulder great trust and discuss the country. Overseas Chinese from all over the world will also come to Beijing, the capital, to give voice to the overseas Chinese community at the meeting. (detailed)

　　Overseas Chinese concern

　　In 2019, the joint enrollment of Jida and Huada was launched.

　　The Admissions Office of Jinan University recently announced the registration instructions for the 2019 Guangzhou entrance examination for students from Hong Kong, Macau, Taiwan Province, overseas Chinese, Chinese and other foreign countries jointly enrolled by Jinan University and Huaqiao University.

　　Eligible candidates can make online name prediction from March 1st to March 29th.

　　112 colleges and universities in the Mainland will enroll Hong Kong students online in advance from March.

　　According to the Hong Kong Business Daily, the Hong Kong Education Bureau announced on the 25th that 112 institutions of higher learning in the Mainland participating in the enrollment plan for Hong Kong students without examination will accept online pre-registration from March 1st. Well-known art schools, such as the Central Conservatory of Music, the Central Academy of Drama and the Central Academy of Fine Arts, have been added, and famous institutions such as Peking University, Tsinghua University and Fudan University are also on the list.

　　According to the enrollment procedure in 2019, colleges and universities can arrange interviews according to candidates’ application materials, and announce the admission list online in late July.

　　China and Algeria will exempt each other from diplomatic visas.

　　After the entry into force of the agreement, China citizens with valid diplomatic and official passports from China will be exempted from visas and can stay for no more than 90 days every 180 days from the date of entry.

　　Those who intend to enter Algeria for work, study, settlement, news reporting and other activities that require the prior approval of the competent authorities of the country should complete the relevant visas before entering Algeria.

　　Thailand will launch e-visa

　　On March 1st, Thailand’s e-visa system will be extended to the consulates general of Thailand in various cities in China, and China citizens who need to travel to Thailand can fill in and submit visa applications online at any time and place through the Internet.

　　After obtaining the online examination and approval from the Immigration Bureau of Thailand, tourists can quickly enter the country from the electronic visa-on-arrival channel with their passports.

　　New domestic regulations

　　Tax reduction of rare disease drugs

　　In order to encourage the development of the pharmaceutical industry with rare diseases and reduce the cost of patients’ medication, the Ministry of Finance, the General Administration of Customs, the State Administration of Taxation and the Food and Drug Administration jointly issued a notice to reduce the value-added tax on the first batch of 21 drugs with rare diseases and 4 APIs by 3% from March 1.

　　New pilot of vocational education reform

　　The Ministry of Education plans to launch a pilot system of "academic certificate+vocational skill level certificate" in vocational colleges and applied undergraduate colleges from March, and encourage students to actively obtain various vocational skill level certificates while obtaining academic certificates; Students choose to participate in vocational skill level certificate training and assessment independently, which is not a restrictive condition for graduation.

　　Activate the new business license

　　The General Administration of Market Supervision issued a notice to activate the new business license from March 1st. The new license maintains the eight formats of the original license; Increase the function of two-dimensional code to facilitate all sectors of society to understand the situation of market players; For the market subject who has received the new paper business license, it is necessary to simultaneously generate the new electronic business license and store it in the electronic business license database.

　　It is more convenient to tax and invoice.

　　In order to optimize the business environment, the State Administration of Taxation decided to further expand the pilot scope of issuing special VAT invoices by small-scale taxpayers from March 1, and to include leasing and business services, scientific research and technical services, residents’ services, repairs and other services. At the same time, the scope of taxpayers who cancel the VAT invoice certification will be extended to all general taxpayers.

　　Implementation of that new patent agency regulation

　　The revised Patent Agency Regulations will come into force on March 1st. The regulations optimize the business environment and relax the access conditions for patent agents and agencies; Improve the way of inspection and supervision, strengthen the supervision of patent agency activities during and after the event: increase the convenience and benefit of the people, and improve the efficiency of patent services.

　　Local scanning

　　Shanghai: Unsold parking spaces in residential areas cannot be sold without rent.

　　The revised "Shanghai Residential Property Management Regulations" will be implemented on March 1. The new regulations make it clear that the parking spaces that have not been sold by the construction unit should be leased to the owners and users to park their vehicles, and they should not refuse to rent them on the grounds that they are only for sale but not for rent; Encourage owners and surrounding units of residential quarters to share parking resources through consultation.

　　Sichuan: Medical insurance for urban workers can be shared with their families.

　　From March 1st, Sichuan Province will implement the new policy of personal account for urban workers’ basic medical insurance, and the personal account funds will be used by their spouses, parents and children of both husband and wife in addition to the employees’ own use, so as to realize the mutual help of family members.

　　Guangdong: Motor vehicles will be restricted in foggy days.

　　The Regulations on the Prevention and Control of Air Pollution in Guangdong Province came into effect on March 1st. The regulations make it clear that some motor vehicles can be restricted when facing heavy polluted weather; The municipal government at or above the prefecture level may, according to the needs of air pollution prevention and control, take measures such as restricting traffic to eliminate high-emission vehicles.

　　Macau: It is forbidden to carry a 30cm selfie stick with you at the airport.

　　From March 1st, Macau International Airport will not allow passengers to bring the following kinds or quantities of articles into the cabin or airport security restricted area in the form of carry-on or hand luggage, including baseball/softball bats and cricket bats, fishing rods, cameras over 30cm after being folded, video tripods, monopods and selfie sticks.

　　These days are worth noting.

　　March 5: Zhou Enlai’s birthday anniversary

　　March 5th: "Learning from Comrade Lei Feng" Memorial Day

　　March 8: International Women’s Day

　　March 12th: the anniversary of Sun Yat-sen’s death

　　March 12th: Arbor Day in China.

　　March 15th: International Consumer Rights Day

　　March 21st: International Day for the Elimination of Racial Discrimination

　　March 21st: World Sleep Day

　　(Source: China Overseas Chinese Network official WeChat, Author: Ran Wenjuan, ID: qiaowangzhongguo)

Dr. Guan Kang Kang You from the Department of Nuclear Medicine talks about thyroid gland.

1. What is pepsinogen?

Pepsinogen (PG) is the precursor of pepsin. According to its biochemical properties and immunogenicity, it can be divided into two subgroups. The immunogenicity of 1~5 components is the same, and it is called Pepsinogen I (PG I), which is mainly secreted by the main cells of gastric fundus gland and mucus neck cells. Components 6 and 7 are called pepsinogen Ⅱ(PGⅡ), which can be secreted by the main cells and mucus neck cells of gastric fundus gland, and also produced by mucus neck cells of pyloric gland of cardiac gland and gastric antrum and upper duodenum.

Usually, about 1% PG enters the blood circulation through the capillary of gastric mucosa, and the PG entering the blood circulation is very stable in the blood. Serum PG ⅰ and PG ⅱ reflect the number of glands and cells in gastric mucosa, and indirectly reflect the secretory function of different parts of gastric mucosa. When pathological changes occur in gastric mucosa, the content of serum PG also changes. Therefore, monitoring the concentration of PG in serum can be used as a means to monitor the status of gastric mucosa.

Detection of pepsinogen (PG), an early warning indicator of gastric cancer

1. Chronic atrophic gastritis is an important "transitional event" in gastric mucosa canceration.

Gastric cancer is one of the common malignant tumors in China, and its mortality ranks first among all kinds of malignant tumors. Its early diagnosis and early treatment have become the only way to improve the quality of life of patients and reduce the mortality. At present, the main methods for diagnosing gastric cancer are fiberoptic gastroscopy and upper gastrointestinal radiography, among which gastroscopy is called the "gold standard" for diagnosing gastric cancer.

At present, it is believed that partial atrophy can be reversed, and once it enters intestinal metaplasia, it is difficult to reverse it. Therefore, there is an urgent need for a tool that can keenly detect the atrophy of gastric mucosa. At this time, the detection of pepsinogen plays a powerful role.

When the gastric fundus gland atrophied, the number of main cells decreased and the level of PG ⅰ decreased. However, because there are more cells secreting PG ⅱ, PG ⅱ can still maintain a high level at this time, and the ratio of PG ⅰ to PG ⅱ decreased significantly. When atrophic gastritis is accompanied by intestinal metaplasia and gastric antrum gland extends to the stomach body, and pseudopyloric metaplasia of gastric fundus gland occurs, the level of PG ⅱ increases more, and the ratio of PG ⅰ to PG ⅱ decreases further. Therefore, the decrease of PG ⅰ level is a reliable sign of gastric fundus gland mucosa atrophy, and PG ⅰ/PG ⅱ profile reflects the degree of gastric fundus gland mucosa atrophy.

2. Helicobacter pylori infection is the initiating factor for the development of gastric cancer.

The occurrence of gastric cancer is the result of multiple factors. The multi-step hypothesis of gastric cancer, that is, from chronic non-atrophic gastritis (formerly known as chronic superficial gastritis) → atrophic gastritis → intestinal metaplasia → intraepithelial neoplasia (formerly known as dysplasia) → gastric cancer, has been generally accepted. Helicobacter pylori (Hp) infection has become the most important initiating factor, and Hp infection has been recognized as an independent risk factor for gastric cancer.

Therefore, active detection of Hp has become one of the important measures to prevent and treat gastric cancer. Hp detection is mainly divided into invasive and non-invasive methods. For Hp-positive infected people, the major guidelines have reached a consensus that Hp infection-related gastritis is an infectious disease and it is recommended to eradicate it.

Hp infection can also significantly affect the serum PG level. At the beginning, PG ⅰ and PG ⅱ both increased, and the increase of PG ⅱ was faster, then PG ⅰ/PG ⅱ decreased, and the larger the Hp infection focus, the greater the decrease of PG ⅰ/PG ⅱ. However, the results of pepsinogen test are lack of specificity, and special Hp test is still needed to judge whether Hp is infected or not.

Third, pepsinogen Ⅰ(PGⅠ),

The results of pepsinogen Ⅱ(PGⅡ) were analyzed as follows:

Four, "pepsinogen" test results misunderstanding:

Myth # 1: If only PG ⅰ is measured during physical examination, nearly 70% of the results are in the range of 40~70ng/mL, which seems to be lower than 70ng/mL on the surface, and gastric atrophy is suspected, but the results are difficult to explain because PG ⅱ and ratio are not measured. When PGⅡ is retested, the ratio of more than 90% is greater than 3. This kind of situation is due to the high incidence of chronic superficial gastritis in China population, which belongs to normal physiological gastric acid secretion insufficiency.

Myth 2: PG-positive means "stomach cancer theory": positive means people at high risk of stomach cancer. PG project is a simple screening project for gastric cancer in the early stage of physical examination, replacing X-ray and ultrasonic screening for gastric cancer. The main significance lies not in diagnosis but in early detection and prevention. Normal people are 15%PG positive, and those with PG positive have a high risk of developing gastric cancer, and the early detection rate of gastric cancer is 1%~2%.

Myth # 3: Pay attention to the change of reference range values of PG ⅰ and PG ⅱ, but not the ratio. Because the secretion of PG ⅰ in gastric mucosa changes greatly (above 70~800ng/mL) under the attack of inflammation, the secretion of PG ⅱ is relatively constant. When comparative value > 3, the degree of PG ⅰ increase can only be combined with clinical analysis to determine the type of gastric diseases. When comparative value < 3, it is suggested that further in-depth endoscopy or pathological sampling should be taken to confirm and warn the high risk of early gastric cancer, and follow-up monitoring should be carried out in the last five years. The incidence of gastric cancer was 2% in PG-positive patients who had no gastric cancer in the same year and in the following five years.

Five, Japan’s experience for reference ("ABC" method+endoscopic screening)

Our neighbor Japan, as a country with high incidence of gastric cancer, has done a very good job in early cancer screening. Their screening strategy for early cancer firmly grasps the two controllable factors of Hp infection and whether gastric fundus gland atrophy occurs.

The Kyoto Consensus of Japan made the following recommendations for the national early cancer screening strategy: first, for Hp infection, the Kyoto Consensus emphasized "shoot to kill", and after everyone sterilized and eradicated Hp, PG was evaluated. The ratio of PG ⅰ/PG ⅱ is ≤3.0, which is regarded as the critical diagnostic value of atrophic gastritis, and as the screening standard of high-risk population of gastric cancer.

Vi. A Long Way to Go-Strategies for Early Cancer Screening in China;

China has a large population base and the incidence of gastric cancer remains high, so it is imperative to find a simple, accurate and effective screening method for gastric cancer. In 2017, the China Consensus on Chronic Gastritis highly affirmed the value of PG, and the guidelines gave the following recommendations: The detection of serum pepsinogen (PG) ⅰ and ⅱ and gastrin -17 may help to judge whether there is gastric mucosal atrophy and its degree. Detection of serum PG ⅰ, PG ⅱ, PG ⅰ/PG ⅱ ratio combined with anti-Hp antibody is helpful for risk stratification management.

The Expert Consensus on Early Gastric Cancer Screening Process in China, published at the end of 2017, not only affirmed the value of serum PG, but also put forward a new gastric cancer screening scoring system, in which the elderly, male, Hp antibody positive, low pepsinogen ratio (PGR) and high serum 17(gastrin-17 (G-17) level are high risk factors for gastric cancer.

Among them, G-17 is a new item in China Guide. G-17 is an amidated gastrin synthesized and secreted by G cells in gastric antrum. Its main physiological function is to stimulate gastric acid secretion and promote the proliferation and differentiation of gastric mucosal cells. G-17 is one of the sensitive indexes to reflect the endocrine function of gastric antrum, which can indicate the atrophy of gastric antrum mucosa or whether there is abnormal proliferation. G-17 itself can also promote the occurrence and development of gastric cancer. When the serum G-17 level rises, it may indicate the risk of gastric cancer.

In addition, different from the Kyoto consensus, the consensus in China put forward the critical value of serological detection for the first time, that is, when PGR<3.89 and G-17> 1.50pmol/L, the risk of gastric cancer increased significantly. The critical value of PGR defined by Kyoto Consensus is ≤3.

According to the score, the guide divides the population into three groups: low risk, medium risk and high risk, and gives the screening strategy.

At the same time, however, we should also see the shortcomings of the China guidelines. The screening population is over 40 years old, and there are other risk factors such as high incidence area of gastric cancer, Hp infection, previous precancerous diseases of gastric cancer, first-degree relatives of gastric cancer patients, diet and so on. However, at present, the onset age of gastric cancer is getting earlier and earlier, and I believe it will definitely enter prospecting stage in the future.

To sum up, serum PG combined with Hp detection is helpful to evaluate the risk of gastric cancer, and can be used as a routine screening method for gastric cancer for ordinary people. However, it cannot replace gastroscopy, and gastroscopy is still strongly recommended for high-risk groups.

Original title: Clinical Significance of Detection of Pepsinogen (PG)

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News from The Paper, Hebei, one of Gree Electric’s important markets, has suffered an unexpected change just as air-conditioning enterprises are preparing for the new freezing year.

It is reported that Hebei Xinxing Gree Electric Sales Co., Ltd. (Hebei Gree), a distributor in Gree Electric, issued a notice on August 18th, saying that on August 16th, Gree Electric suddenly stopped the delivery of goods to Hebei Gree, and asked the distributors who had invested money to plan and pick up the goods as soon as possible.

Just four days after Gree Electric cut off the supply of Gree in Hebei, on August 20th, Xu Zifa, the chairman of Hebei Xinxing Gree Electric Sales Co., Ltd., hosted a banquet for the mainstream distributors in Shijiazhuang five-star hotel, and announced at the meeting that he would quit the operation of Gree from today! At the same time, he promised to give everyone a reassurance, and the dealer’s payment, rebate and anwei fee will be cashed for everyone.

According to a reporter from The Paper who learned from an insider, the details of "Moutai that was drunk for 15 years that night, and 100,000 cash was distributed to 10 people at each table" were true. Xu Zifa also thanked the dealer for his support for so many years.

On August 23rd, a reporter from The Paper called Hebei Gree, and the staff who answered the phone said "there is no obligation to answer whether the company will continue to sell Gree air conditioners" and "if you want to buy Gree air conditioners, the market is everywhere".

Gree Electric also chose to play it cool. As of press time in The Paper, Gree Electric has not responded positively to this matter.

However, The Paper reporter learned from a number of people in the home appliance industry that Gree Electric really fell out with Hebei Gree. Next, Gree Electric will re-establish distribution channels in Hebei.

Some media reported that after Gree stopped supplying to the general distributor in Hebei, Gree Zhuhai Headquarters sent a 50-member marketing team to Hebei, bypassing the original general distribution of Gree in Hebei and contacting local agents. The Paper reporter also learned from insiders that the situation is basically true.

The strength of Hebei Gree should not be underestimated.

Hebei Xinxing Gree Electric Sales Co., Ltd. is one of the most powerful distributors in Gree Electric. Jinghai Internet Technology Development Co., Ltd. (Jinghai Internet), which was established by Hebei Gree and more than a dozen Gree Electric distributors, is an important shareholder of Gree Electric. As of the first quarter of this year, Jinghai Internet holds 8.34% of the shares of Gree Electric, ranking the third largest shareholder.

Tianyancha information shows that Hebei Gree indirectly holds 28% of the shareholders of Jinghai Internet and is also the largest shareholder of Jinghai Internet.

However, on June 24th this year, Gree Electric announced that it had received the Notice of Share Reduction from Jinghai Internet, a shareholder holding more than 5% of the shares. On June 24th, 2022, Jinghai Internet reduced its shareholding by 110,219,217 shares, accounting for 1.86% of the total share capital of Gree Electric, and cashed in 3.5 billion yuan. After the reduction, the shareholding ratio of Jinghai Internet decreased to 6.47%.

More importantly, as a major distributor in Gree Electric, Xu Zifa is also an investor in Philips Air Conditioning, which may also be one of the reasons for the deadlock between the two sides.

On August 9th this year, at the new product launch conference held by Philips Air Conditioning, Huang Hui, the former CEO of Gree Electric, appeared as the chairman of Philips Air Conditioning, Vinfom Hu, the assistant to the former president of Gree Electric, became the president of Philips Air Conditioning, and Xu Zifa attended the meeting as the shareholder representative of Philips Air Conditioning.

Gree turned into a competitor of Gree, which obviously angered Gree.

Liu Buchen, a senior home appliance observer, said in an interview with a reporter from The Paper that Gree Electric must be very dissatisfied with this practice of Hebei Gree. Before that, Gree Electric asked the dealer to choose one, and if he wanted to represent Gree, he could not represent Philips.

"Hebei Gree has both active and passive factors in doing so. Passive factors Gree Electric has promoted channel transformation in recent years, and the proportion of online sales has become higher and higher, which has affected the interests of traditional dealers and forced them to seek new ways out; However, investing in Philips is definitely the initiative of Hebei Gree. Considering so many years of experience and resources, I will try Philips air conditioning. " Liu Buchen said that he is not optimistic about the future prospects of Philips Air Conditioning and will not pose a threat to Gree.

However, Liu Buchen believes that it will take time for Gree to change the Hebei channel and find a suitable candidate, which may have a negative impact on Gree’s local sales.

However, the Hebei dealer incident did not bring much pressure to Gree Electric’s share price. On August 23rd, Gree Electric closed at 30.23 yuan, a decrease of 0.85%. The total market value of Gree Electric is 170.2 billion yuan.

Original title: Drink Maotai and discover gold! Xu Zifa took the lead in Hebei dealers and announced that he would quit Gree and went to Philips.

[Original Truck House] For the 8X4, many friends think that the horsepower above 400 is a bit wasteful, but in the transportation fields such as Lutong and cold chain, the high-horsepower models are growing. The warehouse-grid container has the advantages of large loading capacity and convenient and flexible loading and unloading, and has always been a "generalist" in the freight field. Therefore, in this issue, Xiaobian found four 8×4-drive warehouse trucks with horsepower above 400. Let’s take a look at what sparks can be caused by high horsepower and warehouse boxes, and also provide reference for card friends to choose cars.

"Big Hook 7" is a domestic benchmark in the hearts of many card friends, and the new trucks naturally bring all the excellent qualities they have. First of all, in terms of appearance, this J7 truck is very eye-catching, using a green color scheme, and it also reveals some vitality in its fortitude. China Net adopts a multi-layer point air intake grille with V-shaped decoration, which is very layered and gives people the feeling of strong abdominal muscles, and its appearance is quite amazing.

In terms of power, J7 truck is equipped with CA6DM2-46E6, with a displacement of 11L, a maximum power of 460 HP and a peak torque of 2300N·m, which can output the maximum torque at 1000-1400rpm.

Matching with the engine is the liberated 12-speed manual, the model is CA12TA230M3, and the direct gear design is adopted. The head gear ratio is 15.575, and the highest gear ratio is 1. This is a double countershaft all-aluminum case gearbox developed to meet the needs of light weight, large torque and long life in the market. The service life of the gearbox B10 is 1.5 million kilometers, and the oil change mileage is 100,000 kilometers.

The rear axle of J7 truck is a lightweight 440 rear axle with a speed ratio of 2.867, and the front disc rear wedge brake is adopted.

In terms of chassis configuration, J7 truck adopts the technology of few leaf springs, with two leaf springs on the front axle and four leaf springs on the rear suspension. This technology not only reduces the center of gravity of the whole vehicle, but also increases the cargo capacity by about 2%. The technology of less leaf spring combined with front axle shock absorber makes the driving quality of J7 8×4 truck closer to that of family car.

J7 truck uses brand 12R22.5 size 18-level tubeless and steel rims. The steering wheel is also equipped with maintenance-free oil lubrication wheel end.

The length of the vehicle is 12 meters, the width of the body is 2.55 meters and the height of the body is nearly 4 meters. The size of the car’s matching barn-type jacket is 9.5 meters long and 2.46 meters wide, and the container is also green, fresh and refined. From this angle, we can also see the parking air conditioner on the roof.

The J7 8×4 truck is also equipped with an autonomous air-driven urea system, which has the advantages of simple structure, low failure rate and difficult crystallization.

The cab is naturally the performance of the flagship tractor. With a nearly flat floor, adults with a height of 180cm still have great wealth standing in the cab head space. The four-position steering wheel has multi-function buttons, and the left and right sides can control multimedia and cruise control functions respectively. The main driver’s seat is equipped with an airbag shock-absorbing seat, which has ventilation and heating functions and has a right armrest. The seat belt is also designed in one piece.

The berth space is very spacious, measured at the widest point is about 82cm, the narrowest point is about 76cm, and the thickness of the mattress is 10cm. The real car and the cab that the card friends have spent a lot of time arranging are very western.

The performance of Daguo 7-year-old truck is quite balanced, and it has a high reputation in the eyes of card friends with the good reputation accumulated by tractors. This set of independent power chain configuration, combined with the unique pneumatic urea system, Bridgestone tires, parking air conditioning and rich safety and comfort configuration, makes the J7 truck competitive.

Before the X6000 truck, the X50008X4 trucks are urgent to hit the high-end cargo market.It uses a U-shaped mesh, and the wavy embellishment and chrome trim of the mesh make the trolley look exquisite and resolute. Hawkeye vertical headlights are very energetic, and the light group has LED daytime running and lens, which ensures the paving effect and has less influence on the oncoming traffic.

In terms of power, the X5000 truck is equipped with a 10.5L displacement diesel engine, with a maximum output of 460 HP and a peak torque of 2100 N m. The engine is matched with a 16-speed automatic gearbox.

The rear axle is a 10.5-ton rear axle with a speed ratio of 3.7. Through the calculation of the speed calculator of the truck house, when the engine of the car is 1100-1300 rpm, the gearbox adopts the highest gear, and the speed can reach 75-89km/h, and LaLutong is also very powerful.

Chassis configuration, X5000′ sThe 8X4 truck is equipped withThe 700L aluminum fuel tank can also be equipped with 700+300L double fuel tanks, which is very sufficient for Lutong transportation.

X5000 The dimensions of the 8X4 stockyard truck are 12m long, 2.55m wide and 3.98m high. The size of the matching barn top is 9.5 meters long and 2.45 meters wide.

When I came to the X5000 cab, the texture of the three-color design of black, off-white and logs was in place, and the central control area was designed in layers, with distinct layers. X5000 also uses the flat-bottomed steering wheel that is common in sports passenger cars, which not only models sports, but also makes it easier for card friends to enter and leave the sleeper area in actual use. The gear shifting mechanism adopts the design of holding gear. Due to the lack of manual gear handle, the whole cab looks simple and generous. The central control screen also provides navigation, voice control, air conditioning, Bluetooth, mobile phone interconnection and other functions, which are practical and easy to use.

The airbag shock-absorbing seat equipped with this car is also from Grammer brand, and the adjustment options are very rich. The lumbar back support can be adjusted separately, and the seat ventilation, one-button inflation and deflation, cushion pitch angle and so on are very convenient for the driver to operate.

The sleeper area is also considerable. The width of the sleeper of the X5000 truck is about 90cm, and there is a USB interface and lighting at the bedside. There are curtains between the rear window and the cab to ensure the privacy of the driver when he is resting, which is very humanized.

X5000′ s classic gold power chain of Weichai+Fast+Hand has a good reputation among card friends. With a cab full of texture and a wide berth, the configuration can not be said to be unsatisfactory. Will you give priority to it when you run the green pass transportation?

The next appearance is very eye-catching. It comes from A5W 8X4 warehouse truck. The general appearance of the mecha is very sci-fi, with sharp lines and a sharp-edged feeling. I think this appearance will definitely be favored by young friends. After all, who doesn’t want to drive a truck with a cool appearance?

Truck users have always pursued high timeliness, and have higher requirements for bearing capacity and comfort. However, in the past, tractors were far ahead of contemporary trucks, and the arrival of A5W flagship trucks also made truck users feel full of concern.

In terms of power, A5W truck is equipped with X12NB490 inline six-cylinder diesel engine, with a displacement of 11.8L, a maximum output of 490 horsepower and a peak torque of 2300N·m, which can output the maximum torque at 1000-1400rpm. With such a high horsepower engine on the truck, it is very adaptable to the pursuit of timeliness and complex road conditions.

The gearbox matched with the engine is 12TX2420TD, which is a 12-speed AMT gearbox with direct gear design and the highest gear ratio of 1. The A5W with AMT gearbox has brought more comfortable and relaxed driving experience to the card friends, and running Green Link can save a lot of energy.

The speed ratio of the rear axle of A5W truck is 2.846. It can be calculated by the speed calculator of Truck House that the speed of the car can reach 69-97Km/h in the economic speed range of 1000-1400rpm when the engine adopts the highest gear, which makes it run very fast, which gives it an advantage in speed. This A5W has a very good performance for the transportation scenes such as Lutong, which pursues timeliness.

In terms of chassis configuration, A5W suspension adopts leaf spring suspension, and the number of leaf springs of 3+3+12 reduces the dead weight as much as possible under the condition of ensuring the bearing capacity. Wan Li SFR03 tire is used as the tire, with the specification of 12R22.5. This tire focuses on comprehensive working conditions and wear resistance. Moreover, the aluminum alloy rim is adopted at any cost, which can further reduce the self-weight. Its steering is also equipped with Kangmai visual oil lubrication wheel end, which is worry-free and durable.

In terms of fuel tank, A5W is equipped with an 800L fuel tank, which can bring about 2500 kilometers of endurance for the car. As far as single fuel tank is concerned, this volume ranks among the top models in this inventory.

A5W’s 8X4 stockyard truck is 12m long, 2.55m wide and 3.99m high. On the top, the container of this A5W truck is 9.6m in length and 2.46m in width.

The cab design of A5W is very close to that of flagship tractors K7 and V7 made by Juegel, with excellent texture and ergonomics. There is a large area of leather covering above the center console, and there is even a brushed aluminum decorative board on the air outlet of the air conditioner. The center console is tilted towards the driver as a whole, and all the buttons are within reach.

A5W with flat floor cab is very rich in space, and the bar is far away from the center console, which is very convenient for the driver’s seat to enter and exit. The bar of the car follows the seat, and no matter how the seat moves, the bar is in the most convenient place. And on the right side of the air brake, a kettle rack with a fixed belt is prepared intimately, which is convenient for card friends to store boiled water.

The sleeper area A5W is even wider, with a width of about 1 meter, which ranks among the top models in this inventory. And both ends of the sleeper are also designed with openable windows, which is very convenient for ventilation. Near the rear of the cab, there are also mesh bags and shortcut buttons, which can control the window lifting, interior lighting and so on.

High-horsepower engine, flat-floor cab, AMT automatic transmission and super-wide sleeper, which once appeared in the high-end configuration of tractors, are now equipped on A5W trucks, so that truck riders can also have on-call power, carefree driving experience, comfortable and rich configuration.

The 8X4 truck is a model based on the scenes of high-efficiency green pass, livestock transportation and logistics distribution, and inherits the good reputation of EST in high-end tractors, which is efficient, fuel-efficient and reliable.

The car is equipped with Fukang’s 430 HP engine, which is an in-line six-cylinder diesel engine with a displacement of 11.8L L. The maximum horsepower is 430 HP, the peak torque is 2200N·m, and the maximum torque speed is 1000-1400rpm.

Matching the engine is the Fast 12JSDX240TA gearbox, the shell is made of aluminum alloy, and the overdrive gear is designed, with the head gear ratio of 12.1 and the highest gear ratio of 0.78. The rear axle speed ratio is 3.7.

This EST All the 8X4 trucks are equipped with Jiaan brand tires with specifications of 12.00R2016pr..The steering wheel is also equipped with Kangmai’s long-term maintenance oil to lubricate the wheel end, and the longest oil change cycle is 500,000 kilometers, which can save maintenance costs and further improve the overall attendance rate.

Through the calculation of the speed calculator of the truck house, we can draw that the engine speed of the truck is within the economic speed range, and the speed can reach 76-89km/h when the gearbox adopts the highest gear, which shows the advantages of high efficiency.

In terms of chassis configuration, the suspension of EST 8X4 truck, which focuses on the standard load transport scene, adopts the design of 2+2+4 small leaf springs and straight-through girders, which ensures the bearing capacity and achieves the effect of lightweight body.

The car is equipped with an aluminum alloy fuel tank with a volume of 600L, which is sufficient for medium and long-distance transportation. In terms of body size, the whole length of EST 8X4 truck is 12m, the body width is 2.55m and the body height is 3.95m.. The matching top size of the car is 9.56 meters long and 2.45 meters wide.

EST The interior of the 8X4 truck is the same as that of the EST tractor, and the whole center console is designed in an embracing way, with the middle protruding towards the cab. This makes the function keys near the driver’s side very easy to operate. In the middle of the center console is an air outlet, a power supply interface and a cigarette lighter interface, and the storage island below also provides rich storage spaces such as cup holders, storage compartments and drawers.

The steering wheel of EST truck adopts four-position design, with multi-function buttons and leather package. The whole steering wheel has a very round shape and a thick grip.

The seat of EST truck adopts CVG brand airbag shock-absorbing seat, which is covered with leather and has excellent touch. It can provide the functions of waist and back support adjustment, cushion pitch angle, shock absorption and damping adjustment, rapid inflation and deflation, etc. The seat belt is also an integrated design, which can always follow the driver’s shoulder, which is not easy to wear and is safer.

Fukang truck is equipped with gold transmission combination, lightweight standard-load chassis configuration, and long-term tanker-changing end configuration. This Ou Man EST light truck has made many targeted optimizations to improve attendance and timeliness, so as to meet the needs of market segment users more accurately.

● 　Editor’s note:

In recent years, the progress of domestic trucks in power is obvious to all, and many card friends who pursue high-efficiency transportation begin to turn their attention to high-horsepower models. Even though high-horsepower trucks have advantages that other vehicles can’t catch up with in power, there is no need to blindly pursue high horsepower when returning to the car selection, but it should be determined according to their specific car scenes. Scenes such as green link, cold chain and complex road conditions are the places where high-powered trucks come into play. (Text/Kong Xiangyu Figure/Truck House)