Bian Ce fish and sheep originated from Aofei Temple.

　　Quantum bit report | WeChat official account QbitAI

　　This also cuts the robe, and that also breaks off diplomatic relations. Siraj Raval, the online celebrity of AI, has really become a street rat this time.

　　Moreover, many of them are well-known big names in the industry.

　　After MIT professor Lex Fridman deleted all the content about Siraj from his social media, Jeff Dean, the head of Google AI, also publicly announced that he would take Siraj Raval.

　　Douglas Eck, the chief scientist of Google Brain, took the lead in calling for: this scum, criticize him and take him away!

　　Rachel Thomas, co-founder of fast.ai, regrets it even more:

　　I interviewed Siraj Raval, and it’s a stain on my life.

　　Who is Siraj Raval (Siradj Laval) who was torn by a group of bosses?

　　He is a well-known broadcaster of YouTube, and his AI network course is very popular abroad. If we want to make an analogy, his popularity in English AI online class is just like that of Li Xiaolai in the currency circle.

　　Now, however, the online celebrity native’s design is crumbling. Not only is the paid online course accused of cheating money, but the published paper is also naked plagiarism-all by Ctrl+C and CTRL+V..

　　Before being accused of "cheating money", Siraj still kept his face straight, skipped live as usual, and publicly quoted his own paper.

　　However, unfortunately, Andrew M. Webb, a researcher at Manchester University, took a look at it-is it too insulting to copy and paste the paper like this?

　　Later, the drums broke through thousands of people, and more netizens came off the scene to reveal that Siraj, online celebrity, had no underwear left today …

　　△ skinned stickers reddit heat 2000

　　It is also considered that AI is too hot, and mud and sand are everywhere. Siraj shattered the three views of the AI ? ? community with his own efforts.

　　A popular online class

　　How hot is Siraj? Just look at his former followers: Jeff Dean, Ian Goodfellow, Fran? Ois Chollet… … (All have been cleared)

　　I graduated from Columbia University with a bachelor’s degree (questioned by netizens as a dropout). In 2016, I started uploading artificial intelligence and blockchain related courses on YouTube. Siraj used this style of painting-

　　△ sing rap

　　Known as the strongest Rapper in the AI world.

　　He also founded the School of AI, an AI learning community, and called it a non-profit organization, aiming to provide world-class AI education for anyone on the planet.

　　It is said that more than one million students have seen his online class. And every project he has on GitHub has thousands of stars.

　　△Siraj Raval part GitHub project

　　Three months to learn data science, six weeks of intensive learning … Almost every course is under the banner of rapid learning.

　　Moreover, talking about learning AI to make money is just a title of "The Road to Wealth and Freedom".

　　Because of this resume, eloquence and ability to fool, it was really followed at first, and the business prospects were bright.

　　However, after he launched the charging course Make Money with Machine Learning, Siraj got into trouble.

　　People set a fuse for collapse: using knowledge to pay for cheating money

　　What got Siraj in trouble was an online course he offered, "Making money by machine learning".

　　Just by listening to the name, you can know that this is a knowledge-paid online course that netizens love to see, but the price is not close to the people at all, and it is much more expensive than ordinary courses in Udacity and Coursera. After all the courses are completed, you have to pay 199 US dollars, equivalent to nearly 1300 yuan.

　　He also claimed that his energy was limited, and in order to focus on a few students, he was limited to 500 people.

　　Even so, according to this limit, this course can earn him $100 thousand.

　　Of course, with Siraj’s high popularity, it is definitely not a problem for the course to be full.

　　But the tricky thing began to be exposed.

　　The paid students later found that Siraj not only did not build an exchange group for the course, but also found that some students could not contact each other at all when they tried to communicate through the chat software Slack.

　　This is naturally intentional.

　　Siraj actually adopted the method of building a group in batches, and recruited a total of 1200 students before and after, that is to say, in the name of "limited" marketing, taking advantage of the information gap and secretly expanding enrollment, with the aim of making as much money as possible.

　　Students who know the truth are angry because of "false propaganda", and they also find that the quality and commitment of the course are just like the propaganda at the time of registration.

　　One of the important things is personalized help, which is completely broken.

　　Siraj just released a 30-minute video course every week and gave everyone a question-and-answer period. What about focusing on a few students?

　　More ironically, students find that the course content can be found for free on GitHub … What’s more?

　　Holding something that is free and open source, and then deleting the license to claim originality to make money, itself violates the spirit of the open source community and is despised by the majority of programmers.

　　As a result, students have asked for a refund and dropped out of class, and the momentum is growing.

　　But how can Siraj, who has a good fortune, easily let go of the meat in his mouth? He moved the students to Discord, another chat software, and set up a special program. All messages containing the word "refund" were deleted.

　　If someone goes to his YouTube or Twitter to reply and ask for a refund, Siraj will always black them out.

　　Siraj then added a refund policy to the website, but the requirement is that the refund must be completed within 14 days after registering for the course.

　　However, this obviously violates California law, because consumers have the right to ask for a refund within 30 days.

　　In the end, Siraj couldn’t stand the huge pressure of netizens’ public opinion, or it may be because he was worried about taking a lawsuit. After weighing it again and again, he announced that students who were dissatisfied with the course and paid within 30 days could provide a full refund.

　　Of course, after this battle, the online celebrity people’s establishment collapsed.

　　Lex Fridman, a teacher and researcher at MIT who had been "pink" Siraj before, was also found by netizens last week to quietly delete all the recommendations about Siraj.

　　The paper was found to be plagiarized at pixel level.

　　However, things are not over yet.

　　What completely collapsed Siraj’s design was that he copied other people’s academic papers at pixel level.

　　Below this post, a netizen said that Siraj’s liar nature had long been discovered, especially from his "Neural Qubit" video. In this video, he just summed up the results of Nathan Killoran’s paper and added some subjective and controversial biological theories, but claimed to be his own research.

　　Even the code he posted to GitHub just copied and pasted other people’s versions, and deleted the license and changed some constants.

　　Yesterday, someone even analyzed the differences between Siraj and Nathan Killoran in detail on Twitter, which was equivalent to convicting Siraj of plagiarism.

　　It can be seen that Siraj is almost a piece of plagiarism. The charts, formulas and even symbols used in the two articles are exactly the same.

　　Even careful netizens found that Siraj’s plagiarism can be described as "true pixel level", that is, really taking screenshots.

　　Generally, people who do academic writing will use LaTeX to edit formulas, but the resolution of formulas in Siraj’s paper is actually lower than that in the original paper.

　　Yes, the chart in his paper is so vague. A reasonable explanation is that he just copied and pasted the pictures in other people’s papers.

　　Maybe even "washing the manuscript" feels laborious.

　　Of course, some people say that maybe Siraj doesn’t know LaTeX at all, his college grade is B, and he hasn’t attended graduate school, so he doesn’t have the ability to write professional academic papers.

　　But even if you can’t LaTeX, this plagiarism is too careless. Undergraduate students encounter poor resolution when pasting formulas, and they also know to edit in Word instead of pasting pictures directly.

　　No wonder some people commented that this is simply a plagiarism of Ctrl+C and Ctrl+V levels.

　　Siraj apologizes for his resignation.

　　It is not very nice to say that the expansion of Siraj online courses is just a "just meal" gesture, but copying academic papers and open source code is equivalent to being sentenced to death in the circle.

　　Many big names who had paid attention to Siraj have said that they have cancelled their attention, including Google legend Jeff Dean.

　　An AI enthusiast said that Jeff’s statement is very important. Many people can avoid Siraj’s scam when they see Jeff taking the customs.

　　Siraj saw the momentum, too, and never carried it again.

　　After experiencing a rare silence, in the face of all kinds of evidence dug up by netizens, Siraj finally apologized on his Twitter a few hours ago and deleted the paper suspected of plagiarism on the whole network.

　　However, some people are still kept in the dark, such as the European Space Agency, and even invited him to give a speech at the event.

　　It’s just that there were as many fans as there were at the beginning. Enthusiastic netizens volunteered to set up an "anti-flicker consultation hotline" and sent an email to the European Space Agency, saying that Siraj’s academic ethics was questioned and called for a boycott of his speech.

　　It is also worth noting that Siraj has never forgotten to come to China to collect money over the years.

　　Last year, the domestic blockchain community invited it to cooperate with it, and even called it "Jesus in the machine learning world."

　　Of course, it is not without clues that Siraj misbehaves now.

　　However, because he had a high reputation in the field of machine learning before, and he was too good at marketing, the previous accusations of netizens about his money did not form a momentum.

　　Moreover, Siraj was recognized at first, and it did have something extraordinary. After all, in this field, lively and diverse lecture forms are really unique.

　　However, the motivation is impure, breaking through the bottom line of academic ethics, and trying to make money by using the information gap. In the end, people will inevitably bring about their own destruction.

　　In short, you have to pay it back sooner or later.

　　Fraud in the field of AI will sooner or later be hanged. Right?

　　The author is the signing author of Netease News and NeteaseNo. "Different Attitudes".

This article first appeared on WeChat WeChat official account: Quantum Bit. The content of the article belongs to the author’s personal opinion and does not represent Hexun.com’s position. Investors should operate accordingly, at their own risk.

All relevant units:

　　Recently, after two consecutive cases of positive people were detected in the building where a socially infected person was located in this city, the basic information of all company personnel in the building was not provided, resulting in that the infected person was not required to be isolated at home, but only worked at home. Because the infected person has a trajectory of social activities, it has triggered the risk of social communication. It reflects that there are still some problems in the epidemic prevention and control work of some units, such as unclear base, untrue data and inadequate implementation of responsibilities. In order to further compact the responsibility of the four parties, strengthen the awareness of epidemic prevention, and shoulder the responsibility of epidemic prevention, according to the latest deployment requirements of epidemic prevention and control in the city, the basic ledger and management of personnel in industrial and software information service enterprises in the near future are emphasized as follows:

　　First, strengthen the management of basic information ledger

　　All industrial and software information service enterprises should learn a profound lesson, thoroughly find out the base number of employees (including all kinds of hourly workers, short-term workers, temporary workers, interns, outsourcing, labor dispatch, maintenance, security, cleaning, canteens, related security personnel, etc.), and establish and dynamically update employee basic information accounts (including core information: personnel name, ID number, mobile phone number, detailed current address, family contact, etc.); Optional information: building layout, tenant distribution and contact information of this unit, seat distribution of all personnel’s office space, personnel’s business trip, recent nucleic acid detection, unit gathering activities and meeting organization, visitor record, etc.), and register all kinds of visitors to ensure that the source can be traced and the destination can be traced.

　　Second, make good use of personnel nucleic acid comparison register

　　Adhere to the principle of "all examinations should be carried out" and "all examinations should be carried out", and strengthen the management, tracking and supervision of personnel’s nucleic acid detection. Each industrial enterprise should designate a person to be responsible for strengthening the epidemic prevention management of its staff by using the nucleic acid comparison register, do a good job in information collection and dynamically maintain the register; In addition to regular employees, temporary employees, new employees and related service personnel should also be included in the management scope, and those who leave their jobs should be eliminated in time; It is necessary to promptly urge relevant personnel to carry out nucleic acid testing in accordance with the regulations, effectively control the "entry barrier", prevent risk personnel from entering the place of resumption of work and production, and build a strong internal "firewall" for enterprise epidemic prevention. All districts should check the register in time and urge and guide enterprises that fail to carry out relevant management work as required to carry out testing as required.

　　Third, timely cooperate with the flow adjustment to share the information ledger.

　　Implement the "four early" requirements, once an epidemic situation occurs, find out the risk personnel and points as quickly as possible, truthfully provide the basic information of the full-caliber personnel of the unit, cooperate with the work of tracing the source of flow, screening for landing, investigation and control, and resolutely prevent the leakage of people and the loss of control. If there are home office workers, we should adhere to the principle of "who manages and who is responsible", make overall plans for the specific arrangements and education management of employees’ home office, urge their employees to implement the requirements of community epidemic prevention, report their personal health status and activity track daily, and strictly prevent leakage of management.

　　Four, strictly implement the requirements of normalized nucleic acid screening.

　　Do a good job in the normal nucleic acid detection and screening of "people, things and environment" and regular detection and screening of key departments, key populations and key areas. For 34 key groups such as cold-chain cold storage, imported non-cold-chain goods and security guards, which are involved in the fields of industry and software information services, we should carry out all-out inspection, and carry out nucleic acid testing according to the requirements of their respective industries, including cold-chain cold storage employees once a day, imported non-cold-chain goods employees, security guards and canteen employees once every two days, and other stakeholders with wide contacts should also encrypt the frequency of nucleic acid testing, so as to gain time for finding the epidemic risk at the first time and effectively handling it.

　　I hereby inform you.

Beijing novel coronavirus epidemic prevention and control work leading team　　　　

Resumption of production prevention and control group resumption of production working group　　　　

June 23, 2022　　

　　As the saying goes, "a thousand dollars can’t buy old people to lose weight." Nowadays, many old people have joined the army to lose weight, and it seems that they will be healthy if they lose weight. Recently, a study published in the American Obesity magazine shows that the elderly’s deliberate weight loss may affect their bone health.

　　Body mass index BMI= the square of weight/height, which is an accepted standard to measure obesity. In this study, 77 students with an average BMI of 33.6 (usually 18.5≤ BMI index ≤ 23.9 old people with normal weight, more than 29.9 are severely obese) were given weight-loss intervention for 18 months, and the overall weight of the old people and the bone mineral density of the areas (total hip, femoral neck, lumbar vertebrae and trabecular bone) were monitored and scored at 18 months and 30 months. The results show that the decline of hip bone mineral density will last for one year after weight-loss intervention for elderly obese patients, whether they rebound or not. The study also found that fat loss and weight loss reduced the bone mineral density of hip and increased the risk of osteoporosis.

　　Gou Bo, a professor in the Department of Health Sciences of Xi ‘an Institute of Physical Education, said that if the elderly lose weight improperly, such as excessive diet control, resulting in insufficient nutrition intake, or lose weight too much and too fast, resulting in significant weight loss, it will lead to a decline in bone density. Older people do not have to lose weight if they are only slightly obese and have no obvious cardiovascular disease. If there are some contraindications to exercise, and it is not suitable for exercise to lose weight, you can seek nutrition, medical care and other methods to control your weight under the guidance of a doctor. If obesity is accompanied by other chronic diseases, lose some weight appropriately. In principle, adopt safe and effective methods to achieve the goal at a slower speed such as diet control and exercise.

　　Many old people find that even if they eat and exercise as much as when they were young, it is easy to "gain weight". The reason is that the basal metabolic rate and muscle mass of adults decrease year by year with age. Therefore, even if the elderly eat less, their digestion and absorption ability are poor, and the balance of energy in and out is still "less in and out", in which case it will be "fat".

　　Gou Bo emphasized that obesity will directly affect heart function and vascular health, and it is easy to suffer from various cardiovascular and cerebrovascular diseases. The ideal situation is to "gain muscle and lose fat" on the premise of ensuring basic nutrition.

　　Old people can’t take extreme measures to lose weight, let alone go on a diet like young people. We can start with the moderation and choice of dinner, eat some coarse grains instead of staple food, eat food with high protein content for breakfast, and control the staple food at about 2 Liang at noon. It is not recommended to choose diet pills or surgery to lose weight.

　　In sports, it is suggested that aerobic exercise should be combined with strength training, and it is best to take some soothing forms, such as Tai Ji Chuan, yoga, walking, etc. As long as you can persist every day and achieve a certain amount of exercise, you can lose weight completely.

　　Interviewed expert: Professor Gou Bo, Department of Health Sciences, Xi ‘an Institute of Physical Education

Vision china diagram

News from The Paper, Hebei, one of Gree Electric’s important markets, has suffered an unexpected change just as air-conditioning enterprises are preparing for the new freezing year.

It is reported that Hebei Xinxing Gree Electric Sales Co., Ltd. (Hebei Gree), a distributor in Gree Electric, issued a notice on August 18th, saying that on August 16th, Gree Electric suddenly stopped the delivery of goods to Hebei Gree, and asked the distributors who had invested money to plan and pick up the goods as soon as possible.

Just four days after Gree Electric cut off the supply of Gree in Hebei, on August 20th, Xu Zifa, the chairman of Hebei Xinxing Gree Electric Sales Co., Ltd., hosted a banquet for the mainstream distributors in Shijiazhuang five-star hotel, and announced at the meeting that he would quit the operation of Gree from today! At the same time, he promised to give everyone a reassurance, and the dealer’s payment, rebate and anwei fee will be cashed for everyone.

According to a reporter from The Paper who learned from an insider, the details of "Moutai that was drunk for 15 years that night, and 100,000 cash was distributed to 10 people at each table" were true. Xu Zifa also thanked the dealer for his support for so many years.

On August 23rd, a reporter from The Paper called Hebei Gree, and the staff who answered the phone said "there is no obligation to answer whether the company will continue to sell Gree air conditioners" and "if you want to buy Gree air conditioners, the market is everywhere".

Gree Electric also chose to play it cool. As of press time in The Paper, Gree Electric has not responded positively to this matter.

However, The Paper reporter learned from a number of people in the home appliance industry that Gree Electric really fell out with Hebei Gree. Next, Gree Electric will re-establish distribution channels in Hebei.

Some media reported that after Gree stopped supplying to the general distributor in Hebei, Gree Zhuhai Headquarters sent a 50-member marketing team to Hebei, bypassing the original general distribution of Gree in Hebei and contacting local agents. The Paper reporter also learned from insiders that the situation is basically true.

The strength of Hebei Gree should not be underestimated.

Hebei Xinxing Gree Electric Sales Co., Ltd. is one of the most powerful distributors in Gree Electric. Jinghai Internet Technology Development Co., Ltd. (Jinghai Internet), which was established by Hebei Gree and more than a dozen Gree Electric distributors, is an important shareholder of Gree Electric. As of the first quarter of this year, Jinghai Internet holds 8.34% of the shares of Gree Electric, ranking the third largest shareholder.

Tianyancha information shows that Hebei Gree indirectly holds 28% of the shareholders of Jinghai Internet and is also the largest shareholder of Jinghai Internet.

However, on June 24th this year, Gree Electric announced that it had received the Notice of Share Reduction from Jinghai Internet, a shareholder holding more than 5% of the shares. On June 24th, 2022, Jinghai Internet reduced its shareholding by 110,219,217 shares, accounting for 1.86% of the total share capital of Gree Electric, and cashed in 3.5 billion yuan. After the reduction, the shareholding ratio of Jinghai Internet decreased to 6.47%.

More importantly, as a major distributor in Gree Electric, Xu Zifa is also an investor in Philips Air Conditioning, which may also be one of the reasons for the deadlock between the two sides.

On August 9th this year, at the new product launch conference held by Philips Air Conditioning, Huang Hui, the former CEO of Gree Electric, appeared as the chairman of Philips Air Conditioning, Vinfom Hu, the assistant to the former president of Gree Electric, became the president of Philips Air Conditioning, and Xu Zifa attended the meeting as the shareholder representative of Philips Air Conditioning.

Gree turned into a competitor of Gree, which obviously angered Gree.

Liu Buchen, a senior home appliance observer, said in an interview with a reporter from The Paper that Gree Electric must be very dissatisfied with this practice of Hebei Gree. Before that, Gree Electric asked the dealer to choose one, and if he wanted to represent Gree, he could not represent Philips.

"Hebei Gree has both active and passive factors in doing so. Passive factors Gree Electric has promoted channel transformation in recent years, and the proportion of online sales has become higher and higher, which has affected the interests of traditional dealers and forced them to seek new ways out; However, investing in Philips is definitely the initiative of Hebei Gree. Considering so many years of experience and resources, I will try Philips air conditioning. " Liu Buchen said that he is not optimistic about the future prospects of Philips Air Conditioning and will not pose a threat to Gree.

However, Liu Buchen believes that it will take time for Gree to change the Hebei channel and find a suitable candidate, which may have a negative impact on Gree’s local sales.

However, the Hebei dealer incident did not bring much pressure to Gree Electric’s share price. On August 23rd, Gree Electric closed at 30.23 yuan, a decrease of 0.85%. The total market value of Gree Electric is 170.2 billion yuan.

Original title: Drink Maotai and discover gold! Xu Zifa took the lead in Hebei dealers and announced that he would quit Gree and went to Philips.

Ashton Kutcher, the American movie star who plays Jobs, has just joined Lenovo Group. According to the USA-Today website, Kucher signed a cooperation agreement with Lenovo on the evening of 29th local time to serve as Lenovo’s product engineer and spokesperson.

Lenovo held a new product launch conference in Los Angeles at 7 o’clock that night, and launched the world’s first "legged" tablet computer — — Yoga tablet. The conference was broadcast live on Youtube for global users to watch. At the press conference, Kucher held a Yoga tablet computer, just like the way Jobs introduced Apple’s new products. After the conference, Kucher will meet Lenovo engineers and executives in China in the future.

Kucher introduces Lenovo Yoga tablet computer.

Kucher said at the press conference that modern people often encounter two situations in their daily lives: lying in bed and using a tablet computer is easy to slip into their face because of their hands; The battery of a tablet or smart phone is useless, so everyone has to bring a brick-like mobile power supply. These two common details made the audience laugh, which is indeed an experience that many people have had. The new products launched by Lenovo just solved these two problems: the small bracket liberated people’s hands; The battery life that can work continuously for 18 hours on a single charge can help people reduce the weight of their backpacks. In addition, you can also charge your smartphone with a tablet computer, and the USB interface on the tablet computer can easily achieve this.

Lenovo’s new tablet has 8-inch and 10-inch versions, and the price is $249 and $299 respectively. These two products will be available from October 30, just in time to "play against Taiwan" with the Apple tablet iPad Air, which was officially released on November 1. However, Lenovo’s products are much cheaper than Apple’s iPad Air, and the lowest price of the new generation iPad is $499.

Kucher, 35, graduated from the University of Iowa in the United States, majoring in biochemical engineering (but didn’t graduate). She was once kicked out of her dormitory because she was too noisy and crazy. However, he is now Walden Schmidt, the hero of the popular comedy Two and a Half Heroes, which was launched by CBS in the United States, and also a famous angel investor in Silicon Valley. In addition to Skype, Kucher’s investment also includes Foursquare, Flipboard and Path.

Kucher at the new product launch is very much like Jobs.

Kucher has also cooperated with Google and Apple. When talking about why he joined Lenovo, Kucher said, "Lenovo’s hardware is very, very good. I want to make their products as consumer-friendly as possible. " Kucher will make suggestions on the design and software of Yoga tablet.

USA-Today said that this cooperation is a prepared risk for both sides. And Kucher said that this is precisely the reason why he joined Lenovo. "If you look back on my career, you will find that I have always liked adventure — — Lenovo, too, "Kucher said.

Phoenix. com said that some fruit fans commented that Kucher had joined Lenovo: He should know more about Apple culture after playing Jobs, and now it’s a bit disappointing to advertise Lenovo for money. It seems that he is not a real fruit fan. Since he is not a fruit fan, no wonder he can’t play Jobs well.

Lenovo and Kucher did not disclose the salary of this cooperation.

Stills of the movie Jobs

▍ Source/intranet ▍ Author/Bai Yu

Up nearly 30%! Beijing stands out from the rest, selling cardiovascular and cerebrovascular diseases, tumors and respiratory systems.

In recent years, Chinese medicine industry policies have been introduced frequently, and it has been more favorable since this year. In February, the General Office of the State Council issued the Notice on Several Policies and Measures for Accelerating the Development of Traditional Chinese Medicine. In June, National Medical Products Administration launched ten key research projects, including the research on the effectiveness and safety evaluation of traditional Chinese medicine and the whole process quality control. Real-world data support the research on evaluation methods of traditional Chinese medicine, rare disease treatment drugs, innovation and clinical urgently needed medical devices; National Health Commission and other three departments issued the Opinions on Further Strengthening the Work of Traditional Chinese Medicine in General Hospitals and Promoting the Coordinated Development of Chinese and Western Medicine. On July 7th, official website City, state administration of traditional chinese medicine issued the notice of "Implementation Plan of Traditional Chinese Medicine Cultural Communication Action (2021-2025)", which proposed four key tasks, such as deepening the essence of traditional Chinese medicine culture, so as to further integrate traditional Chinese medicine into public life. According to industry insiders, the Chinese medicine industry continues to usher in favorable policies. While optimizing the industry structure, accelerating inheritance and innovation is conducive to going abroad and further promoting the development of the Chinese medicine industry.

Quarterly sales of Chinese patent medicines in key cities from 2020 to 2021 Q1

Source: terminal competition pattern of Chinese patent medicines in public hospitals in key cities

According to the data of Minenet, in 2020, the sales of proprietary Chinese medicines in public hospitals in key cities will be nearly 30 billion yuan, down more than 10% year-on-year. Judging from the quarterly sales trend, the market gradually picked up after experiencing the low tide in the first quarter of last year, and rose by 29.33% in the first quarter of this year.

Urban Pattern of Chinese Patent Medicines in Public Hospitals of Key Cities in 2021Q1

Source: terminal competition pattern of Chinese patent medicines in public hospitals in key cities

Judging from the urban pattern, Beijing stands out, with sales of nearly 1.8 billion yuan; The sales of Zhengzhou, Chongqing and Guangzhou all exceeded 800 million yuan. From the perspective of TOP20 manufacturers, Zhejiang Kanglaite Pharmaceutical, Yangzijiang Pharmaceutical Group, Shanghai Green Valley Pharmaceutical, Hangzhou Zhongmei Huadong Pharmaceutical and Jichuan Pharmaceutical Group are in the top five; The sales growth rate of Lunan Houpu Pharmaceutical, Tibet Qizheng Tibetan Medicine and Jiangsu Kangyuan Pharmaceutical all exceeded 50%.

From the perspective of large-scale pattern, drugs for cardiovascular and cerebrovascular diseases, drugs for tumor diseases and drugs for respiratory diseases are the hottest, accounting for more than 55% of the total market share; Drugs for musculoskeletal diseases, drugs for pediatrics, drugs for invigorating qi and enriching blood, etc. increased by more than 50%.

The Yangtze River and Jichuan … 16 exclusive products "preempted" TOP20, and 4 products rose by over 30%.

TOP10, a Chinese patent medicine product in public hospitals of key cities in 2021Q1

Source: terminal competition pattern of Chinese patent medicines in public hospitals in key cities

Among TOP20 products, except Shuxuening injection, cinobufotalin capsule, Xingnaojing injection and Tongguanteng injection, 16 products such as Kanglaite injection, Danshen Polyphenolate for injection, Jinshuibao tablet, Suhuang Zhike capsule and Pudilan Xiaoyan oral liquid are exclusive products, involving Zhejiang Kanglaite Pharmaceutical, Shanghai Lvgu Pharmaceutical, Jiangxi Jimin Kexin Pharmaceutical, Yangzijiang Pharmaceutical Group Beijing Haiyan Pharmaceutical, Jichuan Pharmaceutical Group and other manufacturers. In terms of dosage forms, injections account for 60%. From the perspective of treatment categories, cancer diseases are the most commonly used drugs, with 5 drugs; Followed by drugs for cerebrovascular diseases, there are 4; There are three drugs for cardiovascular diseases and three drugs for strengthening waist and strengthening kidney respectively.

From the perspective of sales growth, more than 80% of TOP20 products have positive growth, among which Tongguanteng injection has the fastest growth rate, and cinobufotalin capsules, Xueshuantong for injection (freeze-dried) and Jinshuibao tablets all exceed 30%. It is worth mentioning that only three of the TOP20 products in 2020 are positive growth.

Quarterly sales of Jinshuibao tablets in public hospitals in key cities from 2020 to 2021 Q1 (unit: 10,000 yuan)

Source: terminal competition pattern of Chinese patent medicines in public hospitals in key cities

Jinshuibao tablets are the exclusive products of Jiangxi Jimin Kexin Pharmaceutical. According to the data of Minenet, the sales of Jinshuibao tablets in public hospitals in key cities have increased rapidly in recent years, from less than 50 million yuan in 2017 to more than 400 million yuan in 2020. The sales in the first quarter of this year have exceeded 100 million yuan, a year-on-year increase of 31.02%.

Quarterly sales of Tongguanteng injection (Xiaoaiping injection) in public hospitals in key cities from 2020 to 2021 Q1 (unit: 10,000 yuan)

Source: terminal competition pattern of Chinese patent medicines in public hospitals in key cities

Tongguanteng injection (Xiaoaiping injection) is used for the treatment of esophageal cancer, gastric cancer, liver cancer and other tumors, and is combined with radiotherapy and chemotherapy as adjuvant treatment. According to the data in the Minenet, in 2020, the sales of Tongguanteng injection (Xiaoaiping injection) in public hospitals in key cities exceeded 200 million yuan, up 2.25% year-on-year; The first quarter of this year increased by more than 50% year-on-year. At present, the only manufacturers of this product are Nanjing Shenghe Pharmaceutical and Tonghua Jinma Pharmaceutical Group, among which Nanjing Shenghe Pharmaceutical has the largest market share.

The policy is good! Renfu, Kangyuan, Yiling … Class 1 new drugs launched an impact.

Since 2020, a total of six Chinese patent medicines have been approved for listing. Among them, Lianhua Qingke Tablet is a 6.1-class new Chinese medicine developed by Yiling Pharmaceutical under the guidance of collateral disease theory of traditional Chinese medicine for treating acute tracheobronchitis. Jingu Zhitong Gel is a 6.1-class new Chinese medicine developed on the basis of the clinical experience of Professor Sun Shuchun, an orthopedic expert at China Academy of Traditional Chinese Medicine. Kangyuan Pharmaceutical has independent and complete intellectual property rights of this new medicine. The total alkaloid tablets of Ramulus Mori from Beijing Wuhe Boao Pharmaceutical Co., Ltd. are used to treat type 2. In the first half of this year, Qingfei Detoxification Granule of Institute of Clinical Basic Medicine of Chinese Academy of Traditional Chinese Medicine, Huashi Detoxification Granule of Guangdong Yifang Pharmaceutical and Xuanfei Detoxification Granule of Shandong Buchang Pharmaceutical were approved for listing.

Application for listing of Class I new Chinese patent medicines since 2020

Source: Minenet MED2.0 China Drug Evaluation Database.

In addition, since 2020, a total of 13 Chinese patent medicines have been submitted for listing, among which 10 are Class I new drugs, including Yinqiao Qingre Tablet of Jiangsu Kangyuan Pharmaceutical, Jingule Tablet of Hunan Fangsheng Pharmaceutical, Kunyining Granule of Tasly, Su Xia Jieyu Bufan Capsule of Yiling Pharmaceutical, etc. A few days ago, the total flavonoids capsule of Desmodium styracifolium was submitted to the market as a new class 1.2 Chinese patent medicine and was undertaken by CDE. At present, it is under review and approval, and it is expected to become the first new class 1 Chinese patent medicine in Renfu in recent ten years.

Recently, the news that actor Kathy CHAU passed away at the age of 57 made many people feel sorry, and also made people feel the fragility and impermanence of life.

On December 27th, Kathy CHAU’s sister issued a statement saying that according to the surveillance video and the appraisal of the forensic department, it was comprehensively judged that Kathy CHAU had a sudden heart attack.

For a time, the relationship between female menopause and cardiovascular health has also attracted many people’s attention. Previous studies have pointed out that women after menopause should pay special attention to heart health.

Postmenopausal women

Increased risk of heart disease

Why do women have an increased risk of heart disease after menopause? In fact, this is related to the changes in hormone levels in women.

In 2014, a study on the protective effect of estrogen on women’s cardiovascular system published in China Clinical Journal of Obstetrics and Gynecology pointed out that estrogen plays a very important role in preventing cardiovascular diseases besides regulating reproductive system. The increase of the incidence of coronary heart disease in postmenopausal women is closely related to the significant decrease of estrogen level in postmenopausal women. ①

Previous epidemiological surveys have shown that the age of female coronary heart disease is 10-15 years later than that of male, and the incidence of female coronary heart disease before menopause is only 1/10-3/10 of that of male, but the incidence and mortality of coronary heart disease in postmenopausal women have increased significantly. ②③

In June 2018, a study published in the journal of American Heart Association, Sex Hormones and Cardiovascular Diseases in Postmenopausal Women, also showed that the increase in the ratio of testosterone to estradiol (a kind of estrogen) in postmenopausal women was related to the increased risk of myocardial infarction, stroke and heart failure. The higher the testosterone level, the greater the risk, and the higher the estradiol level, the lower the risk. Every standardized unit of testosterone-estrogen ratio increases the risk of cardiovascular disease by 19%, coronary heart disease by 45% and heart failure by 31%. ④

Heart alarm signal

Be regarded as menopausal discomfort

After menopause, many women mistake some symptoms that may be heart disease, such as chest tightness, wheezing when walking, heart pounding and so on, as the inevitable phenomenon of menopause, but ignore that this may be an alarm signal sent by the heart.

Xu Guochen, former deputy chief physician of the Department of Cardiology, Fourth Medical Center, General Hospital of the People’s Liberation Army, once reminded in a health newspaper article that before menopause, high levels of estrogen in women’s bodies made it difficult for blood vessels to harden and block; After menopause, estrogen in women is greatly reduced, and the heart and blood vessels lack buffering adaptability, so the incidence of cardiovascular diseases rises sharply. In addition, the endocrine level changes in menopause, autonomic nervous dysfunction, there will be upset, sweating and other symptoms, easy to make people mistakenly think that menopause syndrome is not taken seriously. ⑤

Dr. Xu Guochen said that if menopausal women often have symptoms such as extreme fatigue, dizziness, nausea, palpitation, fainting, shortness of breath, chest pain or feeling pressure on their back and upper body, they should pay attention to it and go to the hospital for examination in time.

Sharla Cheung Zhou, chief physician of the Chest Pain Center of Guangdong Provincial Hospital of Traditional Chinese Medicine, published an article on WeChat WeChat official account in Guangdong Provincial Hospital of Traditional Chinese Medicine in 2022, saying that menopausal women have symptoms of palpitation, chest tightness, poor sleep and irritability, so it is best to go to the hospital to have an electrocardiogram first and make a preliminary screening for heart diseases. Sometimes, although the ECG is normal, if there are high-risk factors such as hypertension, hyperlipidemia, diabetes, obesity, smoking, alcoholism and family genetic history of heart disease, it is best to do another exercise load test (that is, running ECG). If there are ischemic changes, it is suspected that you have coronary heart disease, and it is recommended to go to a cardiology specialist for further diagnosis and treatment. ⑥

Health times data map

Women after 50 years old

Take care of your heart.

1. Control physical indicators.

Doctors in Sharla Cheung said that menopause and old age are irresistible, and only by controlling the controllable factors can cardiovascular diseases be effectively prevented. Controlling the controllable factors is that obese people should lose weight properly, smokers and alcoholics should quit smoking and limit alcohol, and patients with hypertension, diabetes and dyslipidemia should control their blood pressure, blood sugar and blood lipids well. ⑥

2. Pay attention to the health of diet

Appropriate supplementation of milk and bean products such as soybean milk, tofu, soybean milk and other foods rich in estrogen and milk with high calcium content. Eating fruits, vegetables and fish is also beneficial food. Avoid eating greasy and full meals, which will increase the burden on the stomach and the risk of obesity.

3. Exercise can delay aging

Proper exercise can delay aging. For postmenopausal women, it is a simple and effective exercise method to take a walk every day and practice Qigong or Baduanjin, but it is based on the principle of not being tired and full of energy after exercise, and remember to persevere.

4. Keep a cheerful mood

Increasing social communication makes people feel happy, which is an important factor in preventing and treating diseases, avoiding being too excited and overworked, so as to avoid too much burden on the heart.

This article is synthesized from:

① Plateau, Huining. Study on the protective effect of estrogen on female cardiovascular system [J]. China Clinical Journal of Obstetrics and Gynecology, 2014(1):3.

②Rosano G, Vitale C, Spoletini l, et al. Cardiovascular health in the menopausal woman: impact of the timing of hormone replacement therapy.Climacteric，2012，15: 299-305

③Huang T,Yang B, Zheng J, et al. Cardiovascular Disease Mortality and Cancer Incidence in Vegetarians: A Meta-Analysis and Systematic Review. Ann Nutr Metab, 2012. 60:233-240.

④Di Zhao, et al. Endogenous Sex Hormones and Incident Cardiovascular Disease in Post-Menopausal Women. J Am Coll Cardiol. Volume 71,Issue 22, June 2018

⑤ June-October, 2013 Health Times "Beware of Heart Alarm after Menopause"

⑥2022-07-07 《 Shaping Heart School | Care for the Heart after Menopause 》 by Guangdong Provincial Hospital of Traditional Chinese Medicine.

Source: Health Times

　　Taurus leaves the year with cold wind, and Jade Tiger welcomes the spring with joy. In the Spring Festival of the Year of the Tiger, CCTV-9 has prepared a rich holiday meal for you, which is carefully arranged and presented, and a large film will accompany you for the New Year!

　　Record to accompany you to watch the Winter Olympics and go to the ice and snow appointment!

　　On the evening of February 4th, Diniger, a cross-country skier of China sports delegation, and Zhao Jiawen, an athlete from nordic combined, jointly lit the main torch of the Beijing Winter Olympics. These two contestants representing China are both after 00, full of youth and unlimited potential.

　　Among them, Zhao Jiawen is the first athlete in the history of China to qualify for the nordic combined Olympic Games. Nordic combined is considered as one of the most difficult snow events. In order to get a ticket to nordic combined in the Beijing Winter Olympics, he pushed himself to the wall and practiced hard, hard and hard again. The exclusive behind-the-scenes about his preparations for the Winter Olympics is in the documentary "Flying over the Ice and Snow Line" which was hit by CCTV-9!

　　The documentary "Flying Over the Ice and Snow Line" was jointly produced by the Film and Television Documentary Center of the General Station and Insight TV of the Netherlands. Ice and snow athletes (teams) from different countries in the world were selected to track and film their struggles in preparing for the 2022 Beijing Winter Olympics, tell their moving stories in their sports careers and real life, and carry forward the sportsmanship of climbing the peak and the lofty feelings of winning glory for their country.

　　Gu Ailing, a talented girl of freestyle skiing in China, Kay Wilby, a famous short track speed skater in the Netherlands, Alice meriwether, an alpine skier in the United States, Donovan Carrillo, a figure skater in Mexico, Katie Ormerod, the Duchess of Artificial Ski Slope in Britain, and Zhao Jiawen, an athlete in nordic combined, China, as the protagonists in the film will bring their wonderful life stories to the audience. The film triggered a warm response after the premiere of CCTV-9, and returned domineering during the Spring Festival, once again shining on the screen.

　　The documentary series "Great Winter" takes the long history of development, sports principles and scientific highlights of the Winter Olympics as the core, and combines the scientific and technological knowledge of the Beijing Winter Olympics venues, scientific training AIDS, etc., with a large number of animation expressions and interesting ways of popular science experts to vividly explain, showing the uniqueness of the Winter Olympics sports from multiple angles and in depth.

　　The micro-documentary "Below Zero" revolves around the 15 events of the Beijing Winter Olympics — — Alpine skiing, biathlon, snowmobile, cross-country skiing, curling, figure skating, freestyle skiing, ice hockey, sleigh, nordic combined, short track speed skating, steel snowmobile, platform skiing, snowboarding, speed skating, etc., with the length of 5 minutes per episode, introduce the most extreme characteristics of a Winter Olympics event and popularize the knowledge of ice and snow sports.

　　Records accompany you to see the mountains and rivers and meet the ultimate China!

　　During the Spring Festival of the Year of the Tiger, two nature documentaries, Meeting the Extreme China and Chasing Fish in the Sea, will show you the ecological beauty and human brilliance in extreme environment from a multi-dimensional perspective.

Stills of "Meeting the Extreme China"

　　"Meeting the Extreme China" is a documentary about China’s most magical natural home, covering seven extreme landscapes of China: from the largest continental glacier in the world — — Puruogangri ice sheet, to the world’s largest mobile desert — — Taklimakan desert; From the extreme cold in the northernmost part of China — — Genhe and Mohe, to the largest and deepest canyon in the world — — Yarlung Zangbo Grand Canyon; From the largest and richest karst landform area in the world — — Karst in southern China, a wonder of the world where rivers flow side by side — — "Three Parallel Rivers" area, and then to the northernmost river confluence sea in China — — Yellow sea and Bohai sea

　　In the most typical season and the most critical moment, the film crew of Meet the Extreme China went deep into these unique extreme places and led the audience to feel the natural power and the miracle of life.

　　The documentary "Chasing Fish in the Sea" fully shows the process of China’s fleet’s offshore fishing, so that the audience can form an overall understanding of the development and progress of offshore fishing in China and feel the professionalism and survival wisdom of "deep-sea hunters". Focusing on offshore fishermen, the film depicts a group of optimistic, fearless, generous and simple "pure men" at sea while presenting their fantastic and arduous journey, which is unforgettable.

　　Record the delicious food with you and start the taste journey!

　　From Baishan Blackwater to the southwest border, from the land of abundance to Guanzhong Plain, the film crew of "The Journey of Pepper" went deep into the frontiers, coasts, plateaus, jungles and cities, and explored the deep-seated reasons why peppers changed the style of Chinese’s food culture while showing regional delicacies related to peppers.

　　How do Jinuo villagers in Xishuangbanna make festive delicious "chopped raw" with peppers? How delicious is the spicy braised duck palm produced in Longyou, Zhejiang Province, which is rich in white pepper? Quanzhou, the starting point of the Maritime Silk Road, has changed from a place that never likes spicy food to a "spicy addiction" resort where Southeast Asian snacks gather. What kind of process has it gone through? I believe you will know after watching this six-episode documentary!

　　"Taste of Macao" is a 4K documentary jointly produced by the Central Radio and Television General Station and the Macao New Port District Federation of Industry and Commerce, with a total of four episodes. After being broadcast on CCTV-1, CCTV-9 and CCTV video at the end of last year, it was well received by the audience and was praised as the "mini-encyclopedia" of Macao food circle. Professor Zhang Tongdao, director of the Documentary Research Center of Beijing Normal University, Ceng Dian praised the film: "The cultural collision carried by food is beautiful and warm, and Taste of Macau is not only a mouth-watering feast, but also a thought-provoking journey."

　　The new film "Taste Expensive and Spicy" and "Four Seasons Flowing New Year’s Eve" was released in the Spring Festival, offering the audience a unique and affectionate New Year’s Eve dinner and expressing Chinese’s deep feelings for the New Year, hometown and home.

　　Chinese New Year is coming, whether you are in a foreign land or returning to your hometown, please come to CCTV-9. Wash the dust in the documentary world, travel across all corners of the country, taste the delicious food on earth, and meet the ultimate China!